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复杂双层-Descemet 内皮下超声乳化在深板层角膜移植术后失败的穿透性角膜移植联合白内障手术中的应用。

Phacoemulsification Under the Complex Dua Layer-Descemet-Endothelium for Combined Cataract Surgery and Penetrating Keratoplasty After Failed Deep Anterior Lamellar Keratoplasty.

机构信息

Department of Ophthalmology, University Magna Græcia of Catanzaro, Catanzaro, Italy.

出版信息

Cornea. 2023 Oct 1;42(10):1297-1300. doi: 10.1097/ICO.0000000000003338. Epub 2023 Jul 4.

DOI:10.1097/ICO.0000000000003338
PMID:37404101
Abstract

PURPOSE

The aim of this study was to report the surgical management of an eye with a cataract and a failed deep anterior lamellar keratoplasty (DALK) graft. Given the null visualization of the anterior chamber, instead of performing penetrating keratoplasty (PK) combined with open-sky extracapsular extraction, the cleavage plane of the previous DALK was used to expose the transparent complex including Dua layer (DL)-Descemet membrane (DM)-endothelium and to perform phacoemulsification in a closed system; then, PK was completed after the surgical removal of the complex DL-DM-endothelium.

METHODS

This study is a case report.

RESULTS

A 45-year-old woman with corneal opacity due to Acanthamoeba keratitis underwent multiple (n = 2) DALK surgeries. The second DALK graft underwent failure, with the development of severe corneal edema; a dense opacity of the lens was also present. The patient was scheduled for combined PK and cataract surgery. Because the cornea was too opaque to allow closed-system cataract surgery, a partial trephination was performed with the purpose of reopening the old donor-host junction and finding the deep cleavage plane. This maneuver permitted the exposition of the complex DL-DM-endothelium that was completely transparent, thus allowing standard phacoemulsification using the phaco-chop technique. A full-thickness corneal graft was then positioned and sutured.

CONCLUSIONS

This case confirms the toughness of the complex DL-DM-endothelium and reveals the transparency of this complex even in the presence of a failed endothelium, thus highlighting distinct advantages of our surgical approach over the conventional one involving PK combined with open-sky extracapsular extraction.

摘要

目的

本研究旨在报告一例白内障合并深板层角膜移植(DALK)失败患者的手术治疗。由于前房无法观察,我们没有进行穿透性角膜移植(PK)联合开放式囊外摘出术,而是利用先前 DALK 的分离平面暴露包括双层(DL)-Descemet 膜(DM)-内皮在内的透明复合体,并在闭合系统中进行超声乳化;然后,在手术切除 DL-DM-内皮复合体后完成 PK。

方法

这是一项病例报告研究。

结果

一名 45 岁女性因棘阿米巴角膜炎导致角膜混浊,曾接受多次(n = 2)DALK 手术。第二次 DALK 移植物失败,出现严重角膜水肿;晶状体也出现致密混浊。患者计划行 PK 联合白内障手术。由于角膜过于混浊,无法进行闭合系统白内障手术,因此进行了部分环钻术,目的是重新打开旧的供体-宿主交界处并找到深层分离平面。这一操作允许暴露完全透明的 DL-DM-内皮复合体,从而可以使用 phaco-chop 技术进行标准的超声乳化。然后放置并缝合全厚角膜移植物。

结论

该病例证实了 DL-DM-内皮复合体的坚韧,并揭示了即使内皮功能丧失,该复合体也具有透明性,这突出了我们的手术方法相对于传统的 PK 联合开放式囊外摘出术的明显优势。

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