Department of Ophthalmology, University Magna Græcia of Catanzaro, Catanzaro, Italy.
Cornea. 2023 Oct 1;42(10):1297-1300. doi: 10.1097/ICO.0000000000003338. Epub 2023 Jul 4.
The aim of this study was to report the surgical management of an eye with a cataract and a failed deep anterior lamellar keratoplasty (DALK) graft. Given the null visualization of the anterior chamber, instead of performing penetrating keratoplasty (PK) combined with open-sky extracapsular extraction, the cleavage plane of the previous DALK was used to expose the transparent complex including Dua layer (DL)-Descemet membrane (DM)-endothelium and to perform phacoemulsification in a closed system; then, PK was completed after the surgical removal of the complex DL-DM-endothelium.
This study is a case report.
A 45-year-old woman with corneal opacity due to Acanthamoeba keratitis underwent multiple (n = 2) DALK surgeries. The second DALK graft underwent failure, with the development of severe corneal edema; a dense opacity of the lens was also present. The patient was scheduled for combined PK and cataract surgery. Because the cornea was too opaque to allow closed-system cataract surgery, a partial trephination was performed with the purpose of reopening the old donor-host junction and finding the deep cleavage plane. This maneuver permitted the exposition of the complex DL-DM-endothelium that was completely transparent, thus allowing standard phacoemulsification using the phaco-chop technique. A full-thickness corneal graft was then positioned and sutured.
This case confirms the toughness of the complex DL-DM-endothelium and reveals the transparency of this complex even in the presence of a failed endothelium, thus highlighting distinct advantages of our surgical approach over the conventional one involving PK combined with open-sky extracapsular extraction.
本研究旨在报告一例白内障合并深板层角膜移植(DALK)失败患者的手术治疗。由于前房无法观察,我们没有进行穿透性角膜移植(PK)联合开放式囊外摘出术,而是利用先前 DALK 的分离平面暴露包括双层(DL)-Descemet 膜(DM)-内皮在内的透明复合体,并在闭合系统中进行超声乳化;然后,在手术切除 DL-DM-内皮复合体后完成 PK。
这是一项病例报告研究。
一名 45 岁女性因棘阿米巴角膜炎导致角膜混浊,曾接受多次(n = 2)DALK 手术。第二次 DALK 移植物失败,出现严重角膜水肿;晶状体也出现致密混浊。患者计划行 PK 联合白内障手术。由于角膜过于混浊,无法进行闭合系统白内障手术,因此进行了部分环钻术,目的是重新打开旧的供体-宿主交界处并找到深层分离平面。这一操作允许暴露完全透明的 DL-DM-内皮复合体,从而可以使用 phaco-chop 技术进行标准的超声乳化。然后放置并缝合全厚角膜移植物。
该病例证实了 DL-DM-内皮复合体的坚韧,并揭示了即使内皮功能丧失,该复合体也具有透明性,这突出了我们的手术方法相对于传统的 PK 联合开放式囊外摘出术的明显优势。