Nguyen Dung Kim, Van Huynh Duong
U1059 INSERM - SAINBIOSE (SAnté INgéniérie BIOlogie St-Etienne), Campus Santé Innovation, Université Jean Monnet, Saint-Priest-en-Jarez, France.
Department of Maxillofacial Surgery, National Hospital of Odonto-Stomatology, Ho Chi Minh, Vietnam.
Imaging Sci Dent. 2023 Jun;53(2):117-126. doi: 10.5624/isd.20220184. Epub 2023 Mar 24.
Odontomas represent a common clinical entity among odontogenic tumors, but are not well-addressed in the Vietnamese population. The present study aimed to determine the clinical and preclinical characteristics of odontomas and associated factors in the Vietnamese population.
This retrospective study retrieved data from histopathological diagnoses from 2 central hospitals of Odonto-Stomatology in Ho Chi Minh City, Vietnam during 2004-2017. The odontomas were classified as complex (CxOD) or compound (CpOD) subtypes. The epidemiological, clinical, and radiological characteristics of the odontomas, stratified by subtype and sex, were obtained and analyzed.
Ninety cases, consisting of 46 CxODs and 44 CpODs, were included. The average age of patients was 32.4 (±20.2) years. The patients with CxOD were older than those with CpOD (<0.05). Clinically, 67% of patients showed an intraoral bone expansion. Approximately 60% of patients with CxOD exhibited a painful symptom, about 3-fold more than those with CpOD (<0.05), whereas almost all patients with CpOD exhibited perturbations of dentition, unlike those with CxOD (<0.05). Radiologically, CxOD was characterized by a larger dimension than CpOD in both sexes (<0.05), and CpOD induced complications in adjacent teeth more often than CxOD (<0.05). The development of odontoma with advancing age differed significantly in odontoma subtypes related to their pathological origins, and between the sexes, resulting from different physiological states.
The findings of this study highlight the value of clinical and radiological features of odontomas and their associated factors for the early diagnosis and adequate treatment of younger patients.
牙瘤是牙源性肿瘤中常见的临床实体，但在越南人群中尚未得到充分研究。本研究旨在确定越南人群中牙瘤的临床和临床前特征及相关因素。
这项回顾性研究检索了越南胡志明市两家口腔专科医院2004年至2017年的组织病理学诊断数据。牙瘤分为复杂型（CxOD）或复合型（CpOD）亚型。获取并分析了按亚型和性别分层的牙瘤的流行病学、临床和放射学特征。
共纳入90例病例，其中46例为CxOD，44例为CpOD。患者的平均年龄为32.4（±20.2）岁。CxOD患者比CpOD患者年龄大（<0.05）。临床上，67%的患者表现为口腔内骨质膨胀。约60%的CxOD患者有疼痛症状，是CpOD患者的3倍左右（<0.05），而几乎所有CpOD患者都有牙列紊乱，与CxOD患者不同（<0.05）。放射学上，CxOD在男女两性中尺寸均大于CpOD（<0.05），CpOD比CxOD更常引起相邻牙齿的并发症（<0.05）。随着年龄增长，牙瘤的发生在与病理起源相关的牙瘤亚型以及男女之间因生理状态不同而有显著差异。
本研究结果突出了牙瘤的临床和放射学特征及其相关因素对年轻患者早期诊断和适当治疗的价值。
