关于非洲南部莱索托类风湿性关节炎的一项人群研究。
A population study on rheumatoid arthritis in Lesotho, southern Africa.
作者信息
Moolenburgh J D, Valkenburg H A, Fourie P B
出版信息
Ann Rheum Dis. 1986 Aug;45(8):691-5. doi: 10.1136/ard.45.8.691.
Abstract
Motivated by the results of a hospital study on rheumatoid arthritis (RA) in Lesotho (southern Africa) a survey of inflammatory polyarthritis (IP) and RA was undertaken in a sample of the rural population of that country. Contrary to expectations the prevalence of IP grades 2-4 (definite disease) was low (0.4%) and equal in both sexes, while probable and definite RA combined (American Rheumatism Association (ARA) criteria) occurred in 1.8% of both males and females. RA was slightly more severe than in other rural African Negro studies but less so when compared with the disease condition of the patients observed in the hospital study. Rheumatoid factor and particularly that directed against heterologous antigen occurred in 41% of the RA patients and in 16% of the controls. Two thirds of the definite cases and 29% of the combined probable and definite group showed radiological abnormalities.
摘要
受莱索托（非洲南部）一家医院关于类风湿关节炎（RA）研究结果的启发，对该国农村人口样本进行了炎症性多关节炎（IP）和RA的调查。与预期相反，2-4级IP（确诊疾病）的患病率较低（0.4%），且男女患病率相等，而可能的RA和确诊的RA合并（美国风湿病协会（ARA）标准）在男性和女性中均为1.8%。与其他非洲农村黑人研究相比，RA的病情略严重，但与医院研究中观察到的患者疾病状况相比则较轻。41%的RA患者和16%的对照组出现类风湿因子，尤其是针对异源抗原的类风湿因子。三分之二的确诊病例以及29%的可能病例与确诊病例合并组显示出放射学异常。
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Rheumatoid arthritis in a rural South African Negro population.南非农村黑人人口中的类风湿性关节炎。
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