注视追随作为婴幼儿新单词学习任务中自闭症的早期诊断标志物。

Gaze Following as an Early Diagnostic Marker of Autism in a New Word Learning Task in Toddlers.

机构信息

Department of Psychology, University of Oviedo, Plaza Feijóo s/n, 33003, Oviedo, Asturias, Spain.

Department of Experimental Psychology, Cognitive Processes and Speech Therapy, University of Complutense of Madrid, Campus de Somosaguas, Pozuelo de Alarcón, 28223, Madrid, Spain.

出版信息

J Autism Dev Disord. 2024 Sep;54(9):3211-3224. doi: 10.1007/s10803-023-06043-1. Epub 2023 Jul 6.

DOI:10.1007/s10803-023-06043-1

PMID:37410255

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11362356/

Abstract

The aim was to test the use of eye-tracking methodology for the early detection of ASD in a task of association between unfamiliar objects and pseudowords. Significant differences were found between ASD (n = 57) and TD (n = 57) Spanish speaking toddlers in the number and time of fixation. The TD children showed more and longer fixations on eyes and mouth while the ASD children attended almost exclusively to objects, making it difficult to integrate lexical and phonological information. Moreover, the TD toddlers looked at the mouth when the pseudoword was produced while the ASD toddlers did not. Gaze fixation on eyes and mouth during word learning recorded by eye-tracking may be used as a biomarker for the early diagnosis of ASD.

摘要

目的是测试眼动追踪方法在一项不熟悉物体与伪词之间关联任务中用于早期检测 ASD 的应用。在注视次数和时间上，ASD（n=57）和 TD（n=57）西班牙语幼儿之间存在显著差异。TD 儿童对眼睛和嘴巴的注视次数更多、时间更长，而 ASD 儿童几乎只关注物体，难以整合词汇和语音信息。此外，当发出伪词时，TD 幼儿会看嘴，而 ASD 幼儿则不会。眼动追踪记录的单词学习过程中对眼睛和嘴巴的注视可能可作为 ASD 的早期诊断生物标志物。