Institute of Angiology Jean Francois Merlen, Frosinone, Italy.
Department of Angiology, ASL Frosinone (Local Unit of the National Health Service), Frosinone, Italy.
Angiology. 2024 Sep;75(8):717-724. doi: 10.1177/00033197231185459. Epub 2023 Jul 6.
Red palms syndrome consists of an intense redness on the palms of the hands and, occasionally, the soles of the feet. This infrequent condition may be primary or secondary. The primary forms are either familial or sporadic. They are always benign and do not require treatment. The secondary forms may have a poor prognosis related to the underlying disease, for which early identification and treatment are imperative. Red fingers syndrome is also rare. It manifests as a persistent redness on the fingers or toes pulp. It is typically secondary either to infectious diseases like human immunodeficiency virus, hepatitis C virus and chronic hepatitis B or to Myeloproliferative Disorders, such as Thrombocythemia and Polycythemia vera. Manifestations spontaneously regress over months or years without trophic alterations. Treatment is limited to that of the underlying condition. Aspirin has been shown effective in Myeloproliferative Disorders.
红掌综合征表现为手掌(偶尔也包括足底)出现弥漫性红斑。这种罕见的疾病可以是原发性的,也可以是继发性的。原发性红掌综合征为家族性或散发性,始终为良性,无需治疗。而继发性红掌综合征可能与潜在疾病相关,预后较差,因此早期识别和治疗至关重要。红手指(趾)综合征也较为罕见,表现为手指(或足趾)腹侧持续性红斑。它通常为继发性,继发于某些传染病,如人类免疫缺陷病毒、丙型肝炎病毒和慢性乙型肝炎,或者骨髓增殖性疾病,如血小板增多症和真性红细胞增多症。数月或数年后,红斑可自发消退,且无营养障碍。治疗仅限于治疗基础疾病。研究表明,阿司匹林对骨髓增殖性疾病有效。