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1
Carboxyl methylation of human erythrocyte band 3 in intact cells. Relation to anion transport activity.完整细胞中人红细胞带3的羧基甲基化。与阴离子转运活性的关系。
Biochem J. 1986 Apr 1;235(1):183-7. doi: 10.1042/bj2350183.
2
Enzymatic methylation of band 3 anion transporter in intact human erythrocytes.完整人红细胞中带3阴离子转运蛋白的酶促甲基化作用
Biochemistry. 1987 Jan 13;26(1):52-9. doi: 10.1021/bi00375a008.
3
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.S-腺苷-L-同型半胱氨酸对完整红细胞中蛋白质羧基甲基化的抑制作用。生理后果。
J Biol Chem. 1984 Jun 10;259(11):7115-22.
4
Role of sulfhydryl groups in band 3 in the inhibition of phosphate transport across erythrocyte membrane in visceral leishmaniasis.巯基在带3中对内脏利什曼病中红细胞膜磷转运抑制作用的角色。
Arch Biochem Biophys. 2005 Apr 1;436(1):121-7. doi: 10.1016/j.abb.2005.01.015.
5
Characterization of phosphoenolpyruvate transport across the erythrocyte membrane. Evidence for involvement of band 3 in the transport system.磷酸烯醇丙酮酸跨红细胞膜转运的特性。关于带3参与转运系统的证据。
Eur J Biochem. 1983 May 16;132(3):531-6. doi: 10.1111/j.1432-1033.1983.tb07394.x.
6
Reversible and irreversible inhibition of phosphate transport in human erythrocytes by a membrane impermeant carbodiimide.一种膜不通透性碳二亚胺对人红细胞中磷酸盐转运的可逆和不可逆抑制作用。
J Biol Chem. 1985 Feb 25;260(4):2404-8.
7
Effect of gossypol on erythrocyte membrane function: specific inhibition of inorganic anion exchange and interaction with band 3.棉酚对红细胞膜功能的影响：对无机阴离子交换的特异性抑制以及与带3蛋白的相互作用。
J Pharmacol Exp Ther. 1985 Sep;234(3):575-83.
8
Kinetic independence between red cell anion exchange and urea transport.红细胞阴离子交换与尿素转运之间的动力学独立性。
Biochim Biophys Acta. 1988 Sep 1;943(3):531-4. doi: 10.1016/0005-2736(88)90386-0.
9
Effects of inorganic and organic anions on the transport of phosphoenol-pyruvate across the erythrocyte membrane.无机和有机阴离子对磷酸烯醇丙酮酸跨红细胞膜转运的影响。
Tokai J Exp Clin Med. 1982;7 Suppl:113-9.
10
Peroxynitrite oxidizes erythrocyte membrane band 3 protein and diminishes its anion transport capacity.过氧亚硝酸盐可氧化红细胞膜带3蛋白并降低其阴离子转运能力。
Free Radic Res. 2007 Mar;41(3):316-23. doi: 10.1080/10715760601090305.

引用本文的文献

1
Protein damage and methylation-mediated repair in the erythrocyte.
Biochem J. 1995 Mar 1;306 ( Pt 2)(Pt 2):313-25. doi: 10.1042/bj3060313.

本文引用的文献

1
Reversible methylation of cytoskeletal and membrane proteins in intact human erythrocytes.
J Biol Chem. 1981 Jun 25;256(12):6102-8.
2
Intrinsic segments of band 3 that are associated with anion transport across red blood cell membranes.与阴离子跨红细胞膜转运相关的带3内在片段。
J Membr Biol. 1980 Dec 15;57(2):95-102. doi: 10.1007/BF01868996.
3
Methylation of membrane proteins in human erythrocytes. Identification and characterization of polypeptides methylated in lysed cells.人红细胞膜蛋白的甲基化。裂解细胞中甲基化多肽的鉴定与表征。
J Biol Chem. 1981 Mar 25;256(6):3067-76.
4
S-adenosyl-L-methionine synthetase from human erythrocytes: role in the regulation of cellular S-adenosylmethionine levels.人红细胞中的S-腺苷-L-甲硫氨酸合成酶：在细胞S-腺苷甲硫氨酸水平调节中的作用。
Biochemistry. 1983 Jun 7;22(12):2978-86. doi: 10.1021/bi00281a030.
5
Methylation of erythrocyte membrane proteins at extracellular and intracellular D-aspartyl sites in vitro. Saturation of intracellular sites in vivo.
J Biol Chem. 1983 Jul 10;258(13):8485-92.
6
Membrane protein carboxyl methylation increases with human erythrocyte age. Evidence for an increase in the number of methylatable sites.膜蛋白羧基甲基化随着人类红细胞的老化而增加。可甲基化位点数量增加的证据。
J Biol Chem. 1983 Jan 25;258(2):1189-96.
7
Inhibition of protein carboxyl methylation by S-adenosyl-L-homocysteine in intact erythrocytes. Physiological consequences.S-腺苷-L-同型半胱氨酸对完整红细胞中蛋白质羧基甲基化的抑制作用。生理后果。
J Biol Chem. 1984 Jun 10;259(11):7115-22.
8
Synthetic peptide substrates for the erythrocyte protein carboxyl methyltransferase. Detection of a new site of methylation at isomerized L-aspartyl residues.用于红细胞蛋白羧基甲基转移酶的合成肽底物。异构化L-天冬氨酰残基上新甲基化位点的检测。
J Biol Chem. 1984 Sep 10;259(17):10722-32.
9
Structure of the serine chemoreceptor in Escherichia coli.大肠杆菌中丝氨酸化学感受器的结构
Nature. 1983;301(5901):623-6. doi: 10.1038/301623a0.
10
Sites of methyl esterification and deamination on the aspartate receptor involved in chemotaxis.参与趋化作用的天冬氨酸受体上的甲酯化和脱氨基位点。
J Biol Chem. 1984 Jun 25;259(12):7719-25.

完整细胞中人红细胞带3的羧基甲基化。与阴离子转运活性的关系。

Carboxyl methylation of human erythrocyte band 3 in intact cells. Relation to anion transport activity.

作者信息

Lou L L, Clarke S

出版信息

Biochem J. 1986 Apr 1;235(1):183-7. doi: 10.1042/bj2350183.

DOI:10.1042/bj2350183
PMID:3741378
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1146666/
Abstract

The anion transport protein of the human erythrocyte membrane, band 3, is reversibly methylated by an endogenous protein carboxyl methyltransferase. The physiological consequence of this modification was studied by measuring the rate of phosphate transport by intact erythrocytes incubated under conditions where protein methylation reactions are inhibited. No change in phosphate transport was detected when cells were treated with either methionine-free media or cycloleucine, whereas cells incubated with adenosine and homocysteine thiolactone displayed a marginally slower rate of transport, which was not reversed by subsequent remethylation of the membrane proteins. These results suggest that erythrocyte protein carboxyl methylation does not directly regulate this activity of band 3.

摘要

人类红细胞膜的阴离子转运蛋白带3可被一种内源性蛋白质羧基甲基转移酶可逆地甲基化。通过测量在蛋白质甲基化反应受到抑制的条件下孵育的完整红细胞的磷酸盐转运速率，研究了这种修饰的生理后果。当细胞用无蛋氨酸培养基或环亮氨酸处理时，未检测到磷酸盐转运的变化，而用腺苷和同型半胱氨酸硫内酯孵育的细胞显示出略微较慢的转运速率，膜蛋白随后的再甲基化并不能逆转这种速率。这些结果表明，红细胞蛋白质羧基甲基化并不直接调节带3的这种活性。