Department of ICU, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu 610072, China.
Department of Critical Care Medicine, Chengdu Second People's Hospital, Chengdu 610072, China.
Transpl Immunol. 2023 Oct;80:101889. doi: 10.1016/j.trim.2023.101889. Epub 2023 Jul 4.
Acute renal injury (AKI) is a common complication of lung transplantation. However, there has been no related research on whether the relationship between fluid balance and input and output influences the occurrence of early AKI. This study aimed to explore the relationship between early fluid balance and input and output on the incidence of early AKI after lung transplantation.
Data from 31 patients who underwent lung transplantation in the Department of Intensive Care Medicine of the Sichuan Academy of Medical Sciences, Sichuan People's Hospital, from August 2018 to July 2021 were collected. To summarize the occurrence of early AKI after lung transplantation, The main indicators of lung transplantation patients were collected. The risk factors for early AKI after lung transplantation were analyzed.
Among the 31 patients who underwent lung transplantation, 21 had early postoperative AKI, with an incidence rate of 67.7%. Compared with the non-AKI group, the hospitalization and ICU hospitalization times of the AKI group were longer (P < 0.05). Multivariate regression analysis showed that intraoperative input volume, BMI, and fluid balance on the first day after lung transplantation were independent risk factors for AKI.
Intraoperative input volume, BMI, and fluid balance on the first day after lung transplantation were independent risk factors for AKI.
急性肾损伤（AKI）是肺移植的常见并发症。然而，目前尚无研究探讨液体平衡和输入与输出之间的关系是否会影响早期 AKI 的发生。本研究旨在探讨肺移植后早期液体平衡和输入与输出与早期 AKI 发生之间的关系。
收集 2018 年 8 月至 2021 年 7 月在四川省医学科学院·四川省人民医院重症医学科行肺移植的 31 例患者的临床资料，总结肺移植术后早期 AKI 的发生情况，收集肺移植患者的主要指标，分析肺移植术后早期 AKI 的危险因素。
31 例行肺移植的患者中，21 例术后早期发生 AKI，发生率为 67.7%。与非 AKI 组比较，AKI 组的住院时间、ICU 住院时间更长（P<0.05）。多因素回归分析显示，术中输入量、BMI 和肺移植术后第 1 天的液体平衡是 AKI 的独立危险因素。
术中输入量、BMI 和肺移植术后第 1 天的液体平衡是 AKI 的独立危险因素。
