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MRI检查阴性的库欣病患者初次手术后垂体及海绵窦探查的手术策略

Surgical strategy of pituitary and cavernous sinus exploration in MRI-Negative Cushing's disease after unsuccessful surgery.

作者信息

Shen Ming, Shou Xuefei, Wang Yongfei

机构信息

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai.

Neurosurgical Institute of Fudan University, Shanghai.

出版信息

Neurosurg Focus Video. 2023 Jul 1;9(1):V6. doi: 10.3171/2023.4.FOCVID2312. eCollection 2023 Jul.

DOI:10.3171/2023.4.FOCVID2312
PMID:37416809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10321543/
Abstract

MRI-Negative Cushing's disease continues to be a challenging disease despite better imaging and techniques. The situation can be more complicated in the setting of prior surgery or failed surgery. Often, a narrow surgical corridor is encountered with robust cavernous or intercavernous sinuses. Controlling venous oozing properly is critical to achieving better outcomes. In this video, the authors present a case of MRI-Negative Cushing's disease after previous unsuccessful surgery. The pituitary tumor was detected on the left side of the gland, close to the cavernous sinus. Margin-plus resection is important if it can be achieved. Biochemical remission was achieved after surgery. The video can be found here: https://stream.cadmore.media/r10.3171/2023.4.FOCVID2312.

摘要

尽管有了更好的成像技术,但MRI阴性库欣病仍然是一种具有挑战性的疾病。在既往手术或手术失败的情况下,情况可能会更加复杂。通常,会遇到狭窄的手术通道以及粗大的海绵窦或海绵间窦。妥善控制静脉渗血对于取得更好的手术效果至关重要。在本视频中,作者展示了一例既往手术失败后MRI阴性库欣病的病例。垂体肿瘤位于腺体左侧,靠近海绵窦。如果能够做到,边缘加切除术很重要。术后实现了生化缓解。视频可在此处查看:https://stream.cadmore.media/r10.3171/2023.4.FOCVID2312 。

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Acta Neurochir (Wien). 2022 Aug;164(8):2105-2114. doi: 10.1007/s00701-022-05267-x. Epub 2022 Jun 10.
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Clin Neurol Neurosurg. 2022 Mar;214:107131. doi: 10.1016/j.clineuro.2022.107131. Epub 2022 Jan 13.
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J Neurosurg. 2019 Jul 1;131(1):122-130. doi: 10.3171/2018.3.JNS18596. Epub 2018 Sep 7.
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