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高锯齿状息肉检出率与结肠镜检查后结直肠癌风险降低相关:来自新罕布什尔州结肠镜检查登记处的数据。

Higher Serrated Polyp Detection Rates Are Associated With Lower Risk of Postcolonoscopy Colorectal Cancer: Data From the New Hampshire Colonoscopy Registry.

机构信息

Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

White River Junction VAMC, White River Junction, Vermont, USA.

出版信息

Am J Gastroenterol. 2023 Nov 1;118(11):1927-1930. doi: 10.14309/ajg.0000000000002403. Epub 2023 Jul 7.

Abstract

INTRODUCTION

We used New Hampshire Colonoscopy Registry data to examine the association between postcolonoscopy colorectal cancer (PCCRC) and sessile serrated detection rates (SSLDRs).

METHODS

We included patients with either a colonoscopy or a CRC diagnosis in the NH State Cancer Registry. PCCRC was any CRC diagnosed ≥ 6 months after index examination.

RESULTS

Of 26,901 patients, 162 were diagnosed with PCCRC. The hazard ratio for PCCRC was lowest for patients whose endoscopists had the highest SSLDR quintile (≥6%) (hazard ratio 0.29; 95% confidence interval 0.16-0.50).

DISCUSSION

Endoscopists with higher SSLDRs had lower risks of PCCRC. These data validate SSLDR as a clinically relevant quality measure.

摘要

简介

我们利用新罕布什尔州结肠镜检查登记数据,研究了结肠镜检查后结直肠癌(PCCRC)与无蒂锯齿状病变检出率(SSLDR)之间的关系。

方法

我们将在 NH 州癌症登记处有结肠镜检查或 CRC 诊断的患者纳入研究。PCCRC 是指在指数检查后≥6 个月诊断出的任何 CRC。

结果

在 26901 名患者中,有 162 名被诊断为 PCCRC。内窥镜医师具有最高 SSLDR 五分位数(≥6%)的患者发生 PCCRC 的风险比最低(风险比 0.29;95%置信区间 0.16-0.50)。

讨论

SSLDR 较高的内窥镜医师发生 PCCRC 的风险较低。这些数据验证了 SSLDR 作为一种临床相关的质量衡量标准。

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