Siminoff R
Biol Cybern. 1986;54(4-5):269-79. doi: 10.1007/BF00318423.
A model of the cone-horizontal cell circuit is presented based on morphological evidence recently found in the Reeves' turtle: a luminosity horizontal cell (LHC) that receives inputs from red-, green-, and blue-sensitive cones in the ratio of 15:3:1, a triphasic horizontal cell (THC) that receives inputs from one class of red-sensitive and from blue-sensitive cones in the ratio of 2:1; and a biphasic chromaticity horizontal cell (BHC) that receives inputs from green-sensitive cones as well as from a special class of red-sensitive (i.e. the broad spectrum) and from blue-sensitive cones in the ratio of 3:2:1. A study of the simulated impulse responses strongly suggests that the basic response patterns of the BHC and THC can be readily explained by a simple wiring diagram consisting of direct hyperpolarizing inputs from the appropriate cones and a depolarizing input from the LHC which acts as a voltage inverter. A negative feedback circuit from the LHC to the cone pedicles is included and its negative feedback gain increases as the mean illuminance level (Io) increases. The negative feedback circuit, which promotes adaptation in the cones to changing Io's, is not necessary for opponent polarization in the BHC or THC, but does explain variabilities of impulse responses.
基于最近在 Reeves 龟中发现的形态学证据，提出了一种视锥 - 水平细胞回路模型：一种亮度水平细胞（LHC），它以 15:3:1 的比例接收来自红敏、绿敏和蓝敏视锥细胞的输入；一种三相水平细胞（THC），它以 2:1 的比例接收来自一类红敏视锥细胞和蓝敏视锥细胞的输入；以及一种双相色度水平细胞（BHC），它以 3:2:1 的比例接收来自绿敏视锥细胞以及一类特殊的红敏（即广谱）视锥细胞和蓝敏视锥细胞的输入。对模拟脉冲响应的研究强烈表明，BHC 和 THC 的基本响应模式可以通过一个简单的接线图轻松解释，该接线图由来自适当视锥细胞的直接超极化输入和来自作为电压逆变器的 LHC 的去极化输入组成。包含了一个从 LHC 到视锥细胞蒂的负反馈回路，并且其负反馈增益随着平均照度水平（Io）的增加而增加。促进视锥细胞适应不断变化的 Io 的负反馈回路对于 BHC 或 THC 中的对立极化不是必需的，但确实解释了脉冲响应的变异性。
