不同脊椎动物物种发育速度的调控。

Regulation of developmental tempo in different vertebrate species.

机构信息

Developmental Biology/Signal Transduction, Max Delbrück Center for Molecular Medicine, Berlin, Germany; NeuroCure Cluster of Excellence, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

出版信息

Cell Stem Cell. 2023 Jul 6;30(7):907-908. doi: 10.1016/j.stem.2023.06.001.

DOI:10.1016/j.stem.2023.06.001

PMID:37419101

Abstract

In this issue, Lazaro et al. use iPSC-derived presomitic mesoderm cells to analyze the oscillatory expression of somitic clock genes. Comparison of a wide range of species, including mouse, rabbit, cattle, rhinoceros, human, and marmoset, demonstrates an excellent correlation between biochemical reaction speed and the tempo of the clock.

摘要

本期中，Lazaro 等人利用 iPSC 来源的体节中胚层细胞分析了体节时钟基因的振荡表达。对包括小鼠、兔、牛、犀牛、人类和狨猴在内的多种物种的广泛比较表明，生化反应速度与生物钟节奏之间存在极好的相关性。