Gaytan F, Bellido C, Aguilar R, Lucena M C
Biol Reprod. 1986 Aug;35(1):219-25. doi: 10.1095/biolreprod35.1.219.
In a morphometric study on the ventral prostate and seminal vesicles in the rat, we investigated the changes in fibromuscular stroma, glandular epithelium, and glandular lumen. Animals were studied at 15, 30 and 45 days of age. The rapid prepubertal growth started earlier in the ventral prostate than in seminal vesicles. In addition, the effects of neonatal administration of estrogens on the different tissue compartments were studied, comparing rats that had been castrated and/or treated with estrogen at birth to intact animals at 15 days of age. Estrogens caused a decrease in the volume of the glandular epithelium and increased the volume of the fibromuscular stroma in both ventral prostate and seminal vesicles. Castration partially abolished the estrogen-induced growth of the stroma, which suggests that the growth is dependent on testicular factors. The difference in proportion of the fibromuscular stroma between the two glands is evidence that the size of the whole seminal vesicles has increased whereas the size of the ventral prostate has decreased.
在一项对大鼠腹侧前列腺和精囊的形态计量学研究中，我们调查了纤维肌性基质、腺上皮和腺腔的变化。对15日龄、30日龄和45日龄的动物进行了研究。青春期前腹侧前列腺的快速生长开始得比精囊更早。此外，研究了新生期给予雌激素对不同组织成分的影响，将出生时阉割和/或用雌激素处理的大鼠与15日龄的完整动物进行比较。雌激素导致腹侧前列腺和精囊中腺上皮体积减小，纤维肌性基质体积增加。阉割部分消除了雌激素诱导的基质生长，这表明这种生长依赖于睾丸因素。两个腺体之间纤维肌性基质比例的差异证明，整个精囊的大小增加了，而腹侧前列腺的大小减小了。
