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2009 年至 2020 年期间,美国成年人出现重度抑郁发作时,自杀行为的发生率上升,且大量患者的治疗需求未得到满足。

Rising Rates of Suicidal Behaviors and Large Unmet Treatment Needs Among US Adults With a Major Depressive Episode, 2009 to 2020.

机构信息

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN.

New England Mental Illness, Research Education, and Clinical Center, VA Connecticut Healthcare System, West Haven, CT.

出版信息

Mayo Clin Proc. 2023 Jul;98(7):969-984. doi: 10.1016/j.mayocp.2023.02.012.

Abstract

OBJECTIVE

To examine recent 12-year trends in the incidence of suicidal ideation (SI) and suicide attempts (SAs) and receipt of mental health treatment among individuals experiencing a past-year major depressive episode (MDE).

PATIENTS AND METHODS

Using data from the National Survey of Drug Use and Health, we estimated the annual percentage of individuals with MDE who reported past-year SI or SAs and their use of mental health services from 2009 to 2020 and calculated odds ratios (ORs) for longitudinal change adjusting for potentially confounding factors.

RESULTS

During our study period, the weighted unadjusted proportion of patients with a past-year MDE who reported SI increased from 26.2% (668,690 of 2,550,641) to 32.5% (1,068,504 of 3,285,986; OR, 1.38; 95% CI, 1.25 to 1.51) and remained significant in the multivariable-adjusted analysis (P<.001). The greatest increase in SI was seen among Hispanic patients, young adults, and individuals with alcohol use disorder. Similar trends were seen for past-year SAs, increasing from 2.7% (69,548 of 2,550,641) to 3.3% (108,135 of 3,285,986; OR, 1.29; 95% CI, 1.04 to 1.61), especially among Black individuals, patients with incomes greater than $75,000, and those with substance use disorders. In multivariable-adjusted analyses, the temporal trend of increasing SI and SAs remained significant (P<.001 and P=0.04, respectively). Among individuals with past-year SI or SAs, there was no notable change in the mental health service use, and over 50% of individuals with MDE and SI (2,472,401 of 4,861,298) reported unmet treatment needs. No notable differences were observed between 2019 and 2020, reflecting the coronavirus disease 2019 pandemic.

CONCLUSION

Among individuals with MDE, rates of SI and SAs have increased, especially among racial minorities and individuals with substance use disorders, without a corresponding change in mental health service use.

摘要

目的

研究过去 12 年来经历过一年期重度抑郁发作(MDE)的个体中出现自杀意念(SI)和自杀尝试(SA)的发生率变化趋势,以及接受心理健康治疗的情况。

患者和方法

利用国家药物使用和健康调查的数据,我们估计了 2009 年至 2020 年期间,报告过去一年存在 SI 或 SA 的 MDE 患者比例,以及他们使用心理健康服务的情况,并对可能存在的混杂因素进行了纵向变化的调整,计算了比值比(OR)。

结果

在研究期间,报告过去一年存在 MDE 且存在 SI 的患者比例,从未调整的加权数据来看,从 26.2%(668690/2550641)上升至 32.5%(1068504/3285986;OR,1.38;95%CI,1.25 至 1.51),且在多变量调整分析中仍然显著(P<.001)。SI 增加最大的是西班牙裔患者、年轻人和有酒精使用障碍的患者。过去一年中 SA 也存在类似的趋势,从 2.7%(69548/2550641)上升至 3.3%(108135/3285986;OR,1.29;95%CI,1.04 至 1.61),尤其是黑人、收入超过 75000 美元的患者和有物质使用障碍的患者。在多变量调整分析中,SI 和 SA 的时间趋势仍然显著(P<.001 和 P=0.04)。在过去一年存在 SI 或 SA 的患者中,心理健康服务的使用没有明显变化,超过 50%的 MDE 和 SI 患者(4861298 人中有 2472401 人)报告存在治疗需求未得到满足。2019 年和 2020 年之间没有明显差异,这反映了 2019 冠状病毒病大流行。

结论

在 MDE 患者中,SI 和 SA 的发生率有所增加,尤其是在少数族裔和有物质使用障碍的患者中,而心理健康服务的使用并没有相应增加。

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