Biomedical Engineering Research Division, School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK.
Sensors (Basel). 2023 Jun 15;23(12):5601. doi: 10.3390/s23125601.
The aim of the study was to test the feasibility of visual-neurofeedback-guided motor imagery (MI) of the dominant leg, based on source analysis with real-time sLORETA derived from 44 EEG channels. Ten able-bodied participants took part in two sessions: session 1 sustained MI without feedback and session 2 sustained MI of a single leg with neurofeedback. MI was performed in 20 s on and 20 s off intervals to mimic functional magnetic resonance imaging. Neurofeedback in the form of a cortical slice presenting the motor cortex was provided from a frequency band with the strongest activity during real movements. The sLORETA processing delay was 250 ms. Session 1 resulted in bilateral/contralateral activity in the 8-15 Hz band dominantly over the prefrontal cortex while session 2 resulted in ipsi/bilateral activity over the primary motor cortex, covering similar areas as during motor execution. Different frequency bands and spatial distributions in sessions with and without neurofeedback may reflect different motor strategies, most notably a larger proprioception in session 1 and operant conditioning in session 2. Single-leg MI might be used in the early phases of rehabilitation of stroke patients. Simpler visual feedback and motor cueing rather than sustained MI might further increase the intensity of cortical activation.
本研究旨在测试基于源分析的实时 sLORETA 从 44 个 EEG 通道引导优势腿视觉神经反馈运动想象 (MI) 的可行性。十名健康参与者参加了两个阶段的实验：阶段 1 为无反馈的持续 MI，阶段 2 为单腿神经反馈的持续 MI。MI 在 20 秒的开启和 20 秒的关闭间隔内进行，以模拟功能磁共振成像。神经反馈以呈现运动皮层的皮层切片形式提供，来自真实运动期间最强活动的频带。sLORETA 处理延迟为 250 毫秒。阶段 1 导致 8-15 Hz 频带的双侧/对侧活动，主要在前额皮质，而阶段 2 导致初级运动皮层的同侧/双侧活动，覆盖与运动执行时相似的区域。有和没有神经反馈的阶段中不同的频率带和空间分布可能反映了不同的运动策略，尤其是在阶段 1 中较大的本体感受和阶段 2 中的操作性条件反射。单腿 MI 可能用于中风患者康复的早期阶段。更简单的视觉反馈和运动提示而不是持续的 MI 可能会进一步增加皮层激活的强度。
