Sarrazin D, Dewar J A, Arriagada R, Benhamou S, Benhamou E, Lasser P, Fontaine F, Travagli J P, Spielmann M, Le Chevalier T
Br J Surg. 1986 Aug;73(8):604-6. doi: 10.1002/bjs.1800730804.
Between 1970 and 1982, 592 patients with T1 and small T2 breast cancers were treated at the Institut Gustave-Roussy by a combination of conservative surgery and radiotherapy. Mean follow-up was 78 months. The actuarial survival rate at 5 and 10 years was 92 per cent and 80 per cent respectively. There were 36 locoregional relapses of which 26 were within the treated breast. The actuarial relapse rate within the breast was 5 per cent at 5 years. If operable, a relapse within the breast did not significantly affect overall survival. The efficacy of conservative management of small breast tumours is confirmed.
1970年至1982年间,古斯塔夫 - 鲁西研究所对592例T1期和小T2期乳腺癌患者采用了保守手术和放疗相结合的治疗方法。平均随访时间为78个月。5年和10年的精算生存率分别为92%和80%。有36例局部区域复发,其中26例发生在接受治疗的乳房内。乳房内的精算复发率在5年时为5%。如果可以手术,乳房内的复发对总生存率没有显著影响。小乳腺肿瘤保守治疗的疗效得到了证实。