对小鼠神经中间叶进行电刺激会引发促黑素细胞激素的钙依赖性分泌。
Electrical stimulation of neurointermediate lobes of mice elicits calcium-dependent output of melanocyte-stimulating hormone.
作者信息
Taraskevich P S, Tomiko S A, Douglas W W
出版信息
Brain Res. 1986 Aug 6;379(2):390-3. doi: 10.1016/0006-8993(86)90797-3.
PMID:3742229
Abstract
Current pulses applied to isolated neurointermediate lobes of mice increased output of melanocyte-stimulating hormone. This response was dependent on extracellular calcium over a wide range of stimulus intensities and thus appears to be a true secretory response from the melanotrophs. Since substantial responses persisted in the presence of tetrodotoxin, much of the effect seems to be independent of Na spiking.
摘要
施加于小鼠离体神经中间叶的电流脉冲增加了促黑素细胞激素的分泌量。在广泛的刺激强度范围内，这种反应依赖于细胞外钙，因此似乎是促黑素细胞的一种真正的分泌反应。由于在存在河豚毒素的情况下仍存在显著反应，大部分效应似乎与钠峰电位无关。
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