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对小鼠神经中间叶进行电刺激会引发促黑素细胞激素的钙依赖性分泌。

Electrical stimulation of neurointermediate lobes of mice elicits calcium-dependent output of melanocyte-stimulating hormone.

作者信息

Taraskevich P S, Tomiko S A, Douglas W W

出版信息

Brain Res. 1986 Aug 6;379(2):390-3. doi: 10.1016/0006-8993(86)90797-3.

DOI:10.1016/0006-8993(86)90797-3
PMID:3742229
Abstract

Current pulses applied to isolated neurointermediate lobes of mice increased output of melanocyte-stimulating hormone. This response was dependent on extracellular calcium over a wide range of stimulus intensities and thus appears to be a true secretory response from the melanotrophs. Since substantial responses persisted in the presence of tetrodotoxin, much of the effect seems to be independent of Na spiking.

摘要

施加于小鼠离体神经中间叶的电流脉冲增加了促黑素细胞激素的分泌量。在广泛的刺激强度范围内,这种反应依赖于细胞外钙,因此似乎是促黑素细胞的一种真正的分泌反应。由于在存在河豚毒素的情况下仍存在显著反应,大部分效应似乎与钠峰电位无关。

相似文献

1
Electrical stimulation of neurointermediate lobes of mice elicits calcium-dependent output of melanocyte-stimulating hormone.对小鼠神经中间叶进行电刺激会引发促黑素细胞激素的钙依赖性分泌。
Brain Res. 1986 Aug 6;379(2):390-3. doi: 10.1016/0006-8993(86)90797-3.
2
Effects of veratridine, tetrodotoxin and other drugs that alter electrical behaviour on secretion of melanocyte-stimulating hormone from melanotrophs of the pituitary pars intermedia.藜芦碱、河豚毒素及其他改变电活动的药物对垂体中间部黑素营养细胞分泌促黑素细胞激素的影响。
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Secretagogue effect of barium on output of melanocyte-stimulating hormone from pars intermedia of the mouse pituitary.钡对小鼠垂体中间部促黑素细胞激素分泌的促分泌作用。
J Physiol. 1983 May;338:243-57. doi: 10.1113/jphysiol.1983.sp014671.
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Effect of dibutyryl cyclic AMP on the release of melanocyte-stimulating hormone from rat neurointermediate lobes in vitro.二丁酰环磷酸腺苷对大鼠神经中间叶体外释放促黑素细胞激素的影响。
J Endocrinol. 1974 Dec;63(3):533-8. doi: 10.1677/joe.0.0630533.
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Calcium signals in melanotrophs and their relation to autonomous secretion and its modification by inhibitory and stimulatory ligands.黑素细胞中的钙信号及其与自主分泌的关系以及抑制性和刺激性配体对其的修饰。
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