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老年主动脉瓣狭窄与经导管主动脉瓣植入术

Aortic stenosis and transcatheter aortic valve implantation in the elderly.

机构信息

BExSc, MD, MMED, Basic Physician Trainee, Royal Hobart Hospital, Hobart, Tas.

MBBS(Hons), BMedSci DipUKMP, GradDipClinLShip, FCSANZ, FRACP, Interventional Cardiologist, Royal Hobart Hospital, Hobart, Tas.

出版信息

Aust J Gen Pract. 2023 Jul;52(7):458-463. doi: 10.31128/AJGP-08-22-6527.

Abstract

BACKGROUND

Severe aortic stenosis (AS) is a condition that commonly affects elderly Australians. Once symptomatic, severe AS has a poor prognosis if untreated. Transcatheter aortic valve implantation (TAVI) is a percutaneous procedure that is now the recommended treatment for elderly patients with severe AS who are suitable for intervention.

OBJECTIVE

This article provides a contemporary review of the diagnosis and management of severe AS in the elderly.

DISCUSSION

Management options for severe AS include TAVI, surgical aortic valve replacement (SAVR), or medical/palliative therapy. In elderly adults, TAVI improves mortality, symptoms and quality of life compared with medical therapy, and is superior to SAVR. The decision regarding which management option is most appropriate for an individual patient is made using a collaborative multidisciplinary approach. General practitioners play key roles in providing information to risk stratify patients when considering intervention, caring for patients after the procedure and/or providing medical and palliative treatment for those deemed unsuitable for intervention.

摘要

背景

严重主动脉瓣狭窄(AS)是一种常见于老年澳大利亚人的疾病。如果未经治疗,出现症状的严重 AS 预后不佳。经导管主动脉瓣植入术(TAVI)是一种经皮手术,现已成为适合介入治疗的老年严重 AS 患者的推荐治疗方法。

目的

本文对老年严重 AS 的诊断和治疗进行了现代综述。

讨论

严重 AS 的治疗选择包括 TAVI、外科主动脉瓣置换术(SAVR)或药物/姑息治疗。在老年人中,与药物治疗相比,TAVI 可降低死亡率、改善症状和生活质量,且优于 SAVR。决定哪种治疗方法最适合个体患者是通过协作的多学科方法做出的。全科医生在考虑介入治疗时为患者提供风险分层信息、术后照顾患者以及为那些不适合介入治疗的患者提供药物和姑息治疗方面发挥着关键作用。

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