Martin S W, Meek A H
Can J Vet Res. 1986 Jan;50(1):15-22.
The principles of path analysis and causal modelling are discussed. Path analysis was applied to three data sets to assess the relationship between group characteristics (number per group and "mixing" subgroups of cattle, feeding-management of the group and processing factors (vaccination and prophylactic antimicrobials) and subsequent morbidity and mortality in feedlot cattle. The major findings agree with previously reported results but the timing and pathways of the effects are elaborated. In general, morbidity in week 1 was correlated with morbidity in week 2, which was correlated with morbidity in weeks 3-5. The same was generally true for mortality. In general, morbidity was not strongly correlated with mortality. Lots (unmixed groups) did not arrive in better condition, but experienced fewer subsequent health problems than mixed groups. (Silage-fed lots appeared to do poorly, however this was apparently due to the positive association between lots and vaccination, the latter being detrimental to mortality rates.) The more cattle per group, the greater the health problems in weeks 3-5 postarrival. Prophylactic antimicrobials in the water supply on arrival lead to increased health problems in the three to five week postarrival period. Antibiotic containing starter rations had a beneficial effect on health status in this period. This effect appeared to be partly due to delaying making silage the major ration component in silage-fed cattle receiving antimicrobial containing starter rations. Vaccination against respiratory disease in either of the first two weeks postarrival had detrimental direct and indirect effects on subsequent health status. Vaccination during weeks 3-5 postarrival was not significantly related to health status in that period.
本文讨论了路径分析和因果建模的原理。路径分析应用于三个数据集,以评估牛群特征(每组数量和牛群的“混合”亚组、牛群的饲养管理)与加工因素(疫苗接种和预防性抗菌药物)之间的关系,以及育肥牛随后的发病率和死亡率。主要研究结果与先前报道的结果一致,但对影响的时间和途径进行了详细阐述。一般来说,第1周的发病率与第2周的发病率相关,第2周的发病率又与第3 - 5周的发病率相关。死亡率情况通常也是如此。一般而言,发病率与死亡率之间的相关性不强。未混合的牛群(批次)入场时状况并不更好,但随后经历的健康问题比混合牛群少。(然而,青贮饲料喂养的牛群表现不佳,这显然是由于批次与疫苗接种之间的正相关关系,而疫苗接种对死亡率不利。)每组牛的数量越多,入场后第3 - 5周出现的健康问题就越多。入场时在供水系统中添加预防性抗菌药物会导致入场后三到五周内健康问题增加。在此期间,含抗生素的开食料对健康状况有有益影响。这种影响似乎部分是由于在接受含抗菌药物开食料的青贮饲料喂养的牛中,延迟将青贮饲料作为主要日粮成分。入场后的前两周内任何一周进行呼吸道疾病疫苗接种都会对随后的健康状况产生有害的直接和间接影响。入场后第3 - 5周进行疫苗接种与该时期的健康状况无显著相关性。