Tanimoto Yuta, Kadokura Makoto, Tanaka Keisuke, Mori Yuki, Takenaka Yumi, Amemiya Fumitake
Department of Gastroenterology, Kofu Municipal Hospital.
Nihon Shokakibyo Gakkai Zasshi. 2023;120(7):610-614. doi: 10.11405/nisshoshi.120.610.
A 79-year-old woman underwent colonoscopy that revealed a 30-mm-sized nodular, mixed-type, lateral spreading tumor-granular in the lower rectum. Endoscopic submucosal dissection was performed, and the pathological findings indicated a mostly adenoma-type tumor with synaptophysin, cluster of differentiation 56-positive, and chromogranin A-negative associated with neuroendocrine carcinoma. Surgical resection was performed owing to vascular invasion, and the lymph node metastasis of the endocrine carcinoma component was observed. Thus, we reported a rare case of the coexistence of adenoma and neuroendocrine carcinoma.
一名79岁女性接受结肠镜检查，发现直肠下段有一个30毫米大小的结节状、混合型、侧向扩散肿瘤颗粒。进行了内镜下黏膜下剥离术，病理结果显示为主要为腺瘤型肿瘤，突触素、分化簇56阳性，嗜铬粒蛋白A阴性，与神经内分泌癌相关。由于血管侵犯进行了手术切除，并观察到内分泌癌成分的淋巴结转移。因此，我们报告了一例腺瘤与神经内分泌癌共存的罕见病例。
