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机器人与胸骨切开术二尖瓣置换术的倾向匹配分析。

Propensity-matched analysis of robotic versus sternotomy approaches for mitral valve replacement.

机构信息

Department of Cardiovascular Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

Department of Nuclear Medicine, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

出版信息

J Robot Surg. 2023 Oct;17(5):2375-2386. doi: 10.1007/s11701-023-01665-0. Epub 2023 Jul 9.

Abstract

To compare early and medium-term outcomes between robotic and sternotomy approaches for mitral valve replacement (MVR). Clinical data of 1393 cases who underwent MVR between January 2014 and January 2023 were collected and stratified into robotic MVR (n = 186) and conventional sternotomy MVR (n = 1207) groups. The baseline data of the two groups of patients were corrected by the propensity score matching (PSM) method. After matching, the baseline characteristics were not significant different between the two groups (standardized mean difference < 10%). Moreover, the rates of operative mortality (P = 0.663), permanent stroke (P = 0.914), renal failure (P = 0.758), pneumonia (P = 0.722), and reoperation (P = 0.509) were not significantly different. Operation, CPB and cross-clamp time were shorter in the sternotomy group. On the other hand, ICU stay time, post-operative LOS, intraoperative transfusion, and intraoperative blood loss were shorter or less in the robot group. Operation, CPB, and cross-clamp time in robot group were all remarkably improved with experience. Finally, all-cause mortality (P = 0.633), redo mitral valve surgery (P = 0.739), and valve-related complications (P = 0.866) in 5 years of follow-up were not different between the two groups. Robotic MVR is safe, feasible, and reproducible for carefully selected patients with good operative outcomes and medium-term clinical outcomes.

摘要

比较机器人和胸骨切开术在二尖瓣置换术(MVR)中的早期和中期结果。收集了 2014 年 1 月至 2023 年 1 月期间接受 MVR 的 1393 例患者的临床数据,并将其分为机器人 MVR(n=186)和传统胸骨切开术 MVR(n=1207)组。通过倾向评分匹配(PSM)方法校正两组患者的基线数据。匹配后,两组患者的基线特征无显著差异(标准化均数差<10%)。此外,手术死亡率(P=0.663)、永久性中风(P=0.914)、肾功能衰竭(P=0.758)、肺炎(P=0.722)和再次手术(P=0.509)的发生率无显著差异。胸骨切开组的手术、CPB 和体外循环时间较短。另一方面,机器人组的 ICU 停留时间、术后 LOS、术中输血和术中出血量较短或较少。机器人组的手术、CPB 和体外循环时间随着经验的增加而显著改善。最后,两组患者在 5 年随访期间的全因死亡率(P=0.633)、二尖瓣再次手术(P=0.739)和瓣膜相关并发症(P=0.866)无差异。机器人 MVR 是安全、可行和可重复的,适用于精心挑选的患者,具有良好的手术结果和中期临床结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ed/10492871/ce876b72f28d/11701_2023_1665_Fig1_HTML.jpg

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