Harahap R E
Cancer Detect Prev. 1986;9(3-4):237-41.
From July, 1977, through December, 1982, 342 patients were evaluated histologically. Aimed biopsy was performed on all cases because of the presence of colposcopic abnormality. Mild dysplasia was regarded as cervical intraepithelial neoplasia grade I (CIN1), moderate dysplasia as CIN2, and severe dysplasia with carcinoma in situ as CIN3. There were 81 CIN1 (24.0%), 32 CIN2 (9.5%), and 33 CIN3 (9.8%) cases. There was no significant influence of the age at first sexual contact, the age at first pregnancy, multiple partnership, sexual frequency, or the age of the patient on the development of CIN. Regular examination should be performed to detect CIN regardless of age, age at first sexual contact, and age at first pregnancy.
从1977年7月至1982年12月，对342例患者进行了组织学评估。由于存在阴道镜异常，对所有病例均进行了靶向活检。轻度发育异常被视为宫颈上皮内瘤变1级（CIN1），中度发育异常为CIN2，重度发育异常伴原位癌为CIN3。有81例CIN1（24.0%）、32例CIN2（9.5%）和33例CIN3（9.8%）病例。首次性接触年龄、首次怀孕年龄、多个性伴侣、性交频率或患者年龄对CIN的发生没有显著影响。无论年龄、首次性接触年龄和首次怀孕年龄如何，都应进行定期检查以检测CIN。
