Kharawala Amrin M, Brahmbhatt Nirav, Bhopalwala Huzefa, Dewaswala Nakeya, Bhopalwala Adnan, Ghumman Waqas, Chait Robert Dean
Medical College, Baroda, Vadodara, India.
Appalachian Regional Healthcare, Whitesburg, KY.
HCA Healthc J Med. 2021 Oct 29;2(5):329-334. doi: 10.36518/2689-0216.1194. eCollection 2021.
Acute pancreatitis (AP) and acute aortic dissection (AAD) are medical emergencies that must be promptly recognized to avoid the development of life-threatening complications. Both of these diseases can present with chest or epigastric pain which can radiate to the back, thus, early suspicion based on clinical presentation and risk factors is essential. We present the case of a 56-year-old patient initially diagnosed with AP who was later found to have an AAD.
A 56-year-old man with a history of alcohol abuse presented with 1 day of diffuse abdominal pain, nausea and vomiting. His lipase was 3,909 U/L and creatinine was 2.19 mg/dL and he was diagnosed with acute alcoholic pancreatitis with acute kidney injury. A non-contrast computed tomography (NCCT) scan of the abdomen showed aortic calcifications. He received 3.8 liters of fluids after which he developed acute respiratory distress requiring intubation. A workup for extracorporeal membrane oxygenation (ECMO) was initiated, given the suspicion of acute respiratory distress syndrome (ARDS) due to pancreatitis. This revealed an AAD with severe aortic regurgitation on transthoracic echocardiography (TTE). CT angiogram showed type A AAD involving the aortic root, ascending aorta, descending aorta, suprarenal and infrarenal abdominal aorta. The celiac axis, superior mesenteric artery (SMA) and inferior mesenteric artery (IMA) were patent.
The patient underwent type A AAD repair with mechanical aortic valve replacement and survived the acute event. His AP resolved and he was discharged home with appropriate follow up.
We hypothesize that if our patient was not assessed for ECMO, the finding of AAD would have been a diagnostic challenge. AP secondary to AAD is rare but a high index of suspicion is required for diagnosis.
急性胰腺炎(AP)和急性主动脉夹层(AAD)均为医疗急症,必须迅速识别以避免危及生命的并发症发生。这两种疾病都可能表现为胸痛或上腹部疼痛,并可放射至背部,因此,基于临床表现和危险因素进行早期怀疑至关重要。我们报告一例最初诊断为AP的56岁患者,后来发现患有AAD。
一名有酗酒史的56岁男性出现弥漫性腹痛、恶心和呕吐1天。他的脂肪酶为3909 U/L,肌酐为2.19 mg/dL,被诊断为急性酒精性胰腺炎伴急性肾损伤。腹部非增强计算机断层扫描(NCCT)显示主动脉钙化。他接受了3.8升液体治疗,之后出现急性呼吸窘迫,需要插管。鉴于怀疑因胰腺炎导致急性呼吸窘迫综合征(ARDS),启动了体外膜肺氧合(ECMO)检查。经胸超声心动图(TTE)显示为AAD伴严重主动脉瓣反流。CT血管造影显示A型AAD累及主动脉根部、升主动脉、降主动脉、肾上腺上方和下方的腹主动脉。腹腔干、肠系膜上动脉(SMA)和肠系膜下动脉(IMA)通畅。
患者接受了A型AAD修复及机械主动脉瓣置换,在急性事件中存活下来。他的AP得到缓解,经适当随访后出院回家。
我们推测,如果未对我们的患者进行ECMO评估,AAD的发现将是一个诊断挑战。AAD继发的AP很少见,但诊断需要高度怀疑指数。