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2017年美国儿科学会临床指南对尼日利亚拉各斯青少年高血压患病率的影响。

Impact of the 2017 AAP clinical guideline on the prevalence of high blood pressure among adolescents in Lagos, Nigeria.

作者信息

Atoh Ifeoma, Ezeogu Joseph, Ekure Ekanem, Omokhodion Samuel Ilenre, Njokanma Fidelis Olisamedua

机构信息

Department of Paediatrics, College of Medicine, University of Lagos, Lagos, Nigeria.

Department of Paediatrics, Federal University Teaching Hospital Owerri, Owerri, Nigeria.

出版信息

Front Pediatr. 2023 Jun 23;11:1184320. doi: 10.3389/fped.2023.1184320. eCollection 2023.

Abstract

INTRODUCTION

Adolescent high blood pressure (HBP) can lead to several end-organ complications if it continues into adulthood. The 2017 AAP Guideline has lower blood pressure cut-off points and consequently leads to the identification of more people with high blood pressure. This study evaluated the impact of the 2017 American Academy of Pediatrics (AAP) Clinical Guideline on the prevalence of high blood pressure among adolescents when compared to the 2004 Fourth Report.

METHODOLOGY

A descriptive cross-sectional study was conducted from August 2020 to December 2020. The selection of 1,490 students, 10-19 years old, was by a two-stage sampling technique. Socio-demographic information and relevant clinical data were obtained using a structured questionnaire. Blood pressure was measured according to standard protocol. Categorical and numerical variables were summarized using frequency, percentages, mean, and standard deviation. The McNemar-Bowker test of symmetry was used to compare the blood pressure values in the 2004 Fourth Report and the 2017 AAP Clinical Guideline. The Kappa statistic was used to test for the degree of agreement between the 2004 Fourth Report and the 2017 AAP Clinical Guideline.

RESULTS

The prevalence rates of high blood pressure, elevated blood pressure, and hypertension among adolescents were 26.7%, 13.8%, and 12.9%, respectively, using the 2017 AAP Clinical Guideline, and 14.5%, 6.1%, and 8.4%, respectively, using the 2004 Fourth Report. The degree of agreement between the 2004 and 2017 guidelines with respect to the classification of blood pressure was 84.8%. The Kappa statistic was 0.71 (CI: 0.67-0.75). The impact of this was a 12.2%, 7.7%, and 4.5% increase in the prevalence of high blood pressure, elevated blood pressure, and hypertension, respectively, using the 2017 AAP Clinical Guideline.

CONCLUSION

The 2017 AAP Clinical Guideline detects a greater proportion of high blood pressure among adolescents. The adoption of this new guideline in clinical practice and its use in the routine screening of high blood pressure among adolescents is recommended.

摘要

引言

青少年高血压若持续至成年期,可能会引发多种终末器官并发症。2017年美国儿科学会(AAP)指南降低了血压临界值,因此可识别出更多高血压患者。本研究评估了与2004年第四次报告相比,2017年美国儿科学会(AAP)临床指南对青少年高血压患病率的影响。

方法

于2020年8月至2020年12月开展了一项描述性横断面研究。采用两阶段抽样技术选取了1490名10至19岁的学生。通过结构化问卷获取社会人口学信息和相关临床数据。按照标准方案测量血压。使用频率、百分比、均值和标准差对分类变量和数值变量进行汇总。采用McNemar-Bowker对称性检验比较2004年第四次报告和2017年AAP临床指南中的血压值。使用Kappa统计量检验2004年第四次报告和2017年AAP临床指南之间的一致性程度。

结果

采用2017年AAP临床指南时,青少年高血压、血压升高和高血压的患病率分别为26.7%、13.8%和12.9%;采用2004年第四次报告时,患病率分别为14.5%、6.1%和8.4%。2004年和2017年指南在血压分类方面的一致性程度为84.8%。Kappa统计量为0.71(95%置信区间:0.67 - 0.75)。这一结果表明,采用2017年AAP临床指南时,高血压、血压升高和高血压的患病率分别增加了12.2%、7.7%和4.5%。

结论

2017年AAP临床指南能检测出更大比例的青少年高血压患者。建议在临床实践中采用这一新指南,并将其用于青少年高血压的常规筛查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1be/10326546/2e75c0b140ce/fped-11-1184320-g001.jpg

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