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局限于腿部的结外自然杀伤/ T细胞淋巴瘤：一例报告

Extranodal Natural Killer/T-cell Lymphoma Isolated to the Leg: A Case Report.

作者信息

Pan Sharon, Mohamed Nada, Saad Saadeddine, Parekh Palak

机构信息

Dermatology, Baylor Scott & White Medical Center - Temple, Temple, USA.

Pathology, Baylor Scott & White Medical Center - Temple, Temple, USA.

出版信息

Cureus. 2023 Jun 5;15(6):e40011. doi: 10.7759/cureus.40011. eCollection 2023 Jun.

DOI:10.7759/cureus.40011
PMID:37425545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10322670/
Abstract

Extranodal natural killer/T-cell lymphoma (ENKTL) is a subtype of non-Hodgkin's lymphoma, and it is exceedingly rare in North America. The "extranasal" subtype of ENKTL frequently involves the skin and typically has an aggressive course with no current standard of treatment available. In this report, we present a case of cutaneous ENKTL in an otherwise healthy middle-aged male.

摘要

结外自然杀伤细胞/T细胞淋巴瘤（ENKTL）是非霍奇金淋巴瘤的一种亚型，在北美极为罕见。ENKTL的“鼻外”亚型常累及皮肤，通常病程侵袭性强，目前尚无标准治疗方案。在本报告中，我们介绍了一例原本健康的中年男性皮肤ENKTL病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88c/10322670/d266bf0b0329/cureus-0015-00000040011-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88c/10322670/f70dcbdeff53/cureus-0015-00000040011-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88c/10322670/132230c62ca0/cureus-0015-00000040011-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88c/10322670/55c3e5923004/cureus-0015-00000040011-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88c/10322670/d266bf0b0329/cureus-0015-00000040011-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88c/10322670/f70dcbdeff53/cureus-0015-00000040011-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88c/10322670/132230c62ca0/cureus-0015-00000040011-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88c/10322670/55c3e5923004/cureus-0015-00000040011-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c88c/10322670/d266bf0b0329/cureus-0015-00000040011-i04.jpg

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本文引用的文献

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Skin diseases in Asian individuals that you do not want to miss: A selection of unique or relatively more common conditions in Asian populations.亚洲人群中不容错过的皮肤疾病：亚洲人群中一些具有独特性或相对更为常见的皮肤疾病。
Clin Dermatol. 2021 Sep-Oct;39(5):879-886. doi: 10.1016/j.clindermatol.2021.05.023. Epub 2021 May 18.
2
Diagnosis and prognostic stratification of cutaneous lymphoma.皮肤淋巴瘤的诊断和预后分层。
J Dermatol. 2022 Feb;49(2):210-222. doi: 10.1111/1346-8138.16099. Epub 2021 Aug 4.
3
Extranodal NK/T cell lymphoma, nasal type: An updated overview.
结外 NK/T 细胞淋巴瘤，鼻型：最新综述。
Crit Rev Oncol Hematol. 2021 Mar;159:103237. doi: 10.1016/j.critrevonc.2021.103237. Epub 2021 Jan 22.
4
Cutaneous extranodal natural killer (NK) / T - cell lymphoma: A comprehensive clinical features and outcomes analysis of 71 cases.皮肤结外自然杀伤（NK）/T 细胞淋巴瘤：71 例综合临床特征和结局分析。
Leuk Res. 2020 Jan;88:106284. doi: 10.1016/j.leukres.2019.106284. Epub 2019 Nov 30.
5
Combined use of DDGP and IMRT has a good effect on extranodal natural killer/T-cell lymphoma, nasal type.DDGP与调强适形放疗（IMRT）联合应用对鼻型结外自然杀伤/T细胞淋巴瘤有良好疗效。
Hematol Oncol. 2020 Feb;38(1):103-105. doi: 10.1002/hon.2637. Epub 2019 Dec 1.
6
Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Basic Science and Clinical Progress.结外鼻型自然杀伤/T细胞淋巴瘤：基础科学与临床进展
Front Pediatr. 2019 Apr 16;7:141. doi: 10.3389/fped.2019.00141. eCollection 2019.
7
Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL-NT): An Update on Epidemiology, Clinical Presentation, and Natural History in North American and European Cases.结外NK/T细胞淋巴瘤，鼻型（ENKTL-NT）：北美和欧洲病例的流行病学、临床表现及自然史最新进展
Curr Hematol Malig Rep. 2016 Dec;11(6):514-527. doi: 10.1007/s11899-016-0355-9.
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Extra-nodal natural killer/T cell lymphoma in elderly patients: the impact of aging on clinical outcomes and treatment tolerability.老年患者的结外自然杀伤/T细胞淋巴瘤：衰老对临床结局和治疗耐受性的影响。
Ann Hematol. 2016 Mar;95(4):581-91. doi: 10.1007/s00277-015-2581-y. Epub 2016 Jan 4.
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