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新型冠状病毒肺炎(COVID-19)住院患者、门诊患者的会诊重症和非重症病例的皮肤黏膜表现以及疫苗相关皮肤病:来自伊朗两个综合COVID-19中心的临床图谱及大型原创研究

Mucocutaneous presentations of consultant critical and non-critical cases of admitted COVID-19 patients, outpatients, and vaccine-associated dermatoses: a clinical atlas and a large original study of two general COVID-19 centers from Iran.

作者信息

Sadeghzadeh-Bazargan Afsaneh, Goodarzi Azadeh

机构信息

Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center, School of Medicine, Iran University of Medical Sciences, Tehran, IranUniversity of Medical Sciences, Tehran, Iran.

出版信息

Dermatol Reports. 2023 May 23;15(2):9473. doi: 10.4081/dr.2023.9473. eCollection 2023 Jun 7.

Abstract

Rapid and proper diagnosis of mucocutaneous presentations of COVID-19 which in many cases are representing internal organ damage is a key way to better approach these patients, and it could be even lifesaving. In this original study, we reported consultant critical and non-critical cases of admitted COVID-19 patients and some interesting outpatient cases for 14 months, and some newly encountered vaccine-associated dermatoses. We presented 121 cases divided into 12 categories; all had full multi-aspects photographs attached as an atlas to a . These categories were:1- Generalized papulopustular eruptions (3 patients), 2- Erythroderma (4 patients), 3- Maculopapular lesions(16 patients), 4- Mucosal lesions (8 patients), 5- Urticarial lesions and angioedema (16 patients), 6- Vascular injuries (22 patients), 7- Vesiculobullous lesions (12 patients), 8- The specific new onset of mucocutaneous presentations or aggravation of any especial previous dermatoses (9 patients), 9- Nail changes (3 patients), 10- Hair loss (2 patients), 11- Non-specific mucocutaneous problems (16 patients) and 12-Vaccine-associated dermatoses (10 patients).In the pandemic, if we countered with extensive mucocutaneous lesions with vascular components or vesiculobullous erosive lesions in association with any cutaneous rash that could be an alarming sign of a probable life-threatening systemic event, we would need to approach them as soon as possible.

摘要

快速且准确地诊断新型冠状病毒肺炎(COVID-19)的皮肤黏膜表现(在许多情况下,这些表现代表着内部器官损伤)是更好地诊治这些患者的关键途径,甚至可能挽救生命。在这项原创性研究中,我们报告了14个月内收治的COVID-19患者的重症和非重症病例以及一些有趣的门诊病例,还有一些新发现的疫苗相关皮肤病。我们展示了121个病例,分为12类;所有病例都附有全面的多方面照片,作为图谱附于[未明确内容处]。这些类别包括:1 - 泛发性丘疹脓疱性皮疹(3例患者),2 - 红皮病(4例患者),3 - 斑丘疹病变(16例患者),4 - 黏膜病变(8例患者),5 - 荨麻疹样病变和血管性水肿(16例患者),6 - 血管损伤(22例患者),7 - 水疱大疱性病变(12例患者),8 - 皮肤黏膜表现的新出现或既往任何特殊皮肤病的加重(9例患者),9 - 指甲改变(3例患者),10 - 脱发(2例患者),11 - 非特异性皮肤黏膜问题(16例患者)和12 - 疫苗相关皮肤病(10例患者)。在疫情期间,如果我们遇到伴有血管成分的广泛皮肤黏膜病变或水疱大疱性糜烂性病变,且伴有任何皮疹,这可能是潜在危及生命的全身性事件的警示信号,我们需要尽快对其进行诊治。

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