Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain.
Mental Health Unit, Regional University Hospital, Málaga, Spain.
Prim Health Care Res Dev. 2023 Jul 10;24:e45. doi: 10.1017/S1463423623000300.
The aim of this study was to evaluate the impact of a multifaceted intervention to implement an adapted guideline for the management of depression in primary health care.
A hybrid trial was carried out to determine the effect of a multicomponent provider-centred intervention to improve the detection and diagnosis of depression in primary care, as part of the guideline implementation process, and to collect information about barriers and facilitators in a real-world context. Before the multicomponent intervention, a descriptive cross-sectional study was performed to assess the population prevalence of depression in the participating health centres and to detect possible differences. Subsequently, a quasi-experimental two-phase study was carried out with a concurrent control group to assess the impact of the multicomponent intervention on the main outcomes (detection of depression, evaluation of its severity and the use of structured methods to support the diagnosis).
Nine-hundred seventy-four patients took part in the first phase. According to their clinical records, the prevalence of depression ranged from 7.2% to 7.9%, and there were no significant differences between the health centres scheduled to receive the intervention and those in the control group. In the experimental phase, 797 randomly selected participants received the multicomponent intervention. Adjusted multivariable analysis performed before the implementation revealed no significant differences in depression between the experimental and control groups. However, after the intervention, modest but significant differences were observed, which persisted at 1 year after the intervention.
A multicomponent intervention for the implementation of a clinical guideline for the management of depression in primary care produced improvements in the identification of depression and in the degree of severity recorded.
本研究旨在评估一项多方面干预措施对在初级保健中实施适应指南管理抑郁症的影响。
开展了一项混合试验,以确定多组分以提供者为中心的干预措施对改善初级保健中抑郁症的检测和诊断的效果,作为指南实施过程的一部分,并在真实环境中收集有关障碍和促进因素的信息。在多组分干预之前,进行了描述性横断面研究,以评估参与卫生中心的人群中抑郁症的流行情况,并发现可能存在的差异。随后,进行了准实验两阶段研究,具有同期对照组,以评估多组分干预对主要结局(抑郁症的检测,其严重程度的评估和使用结构化方法支持诊断)的影响。
第一阶段有 974 名患者参加。根据他们的临床记录,抑郁症的患病率在 7.2%至 7.9%之间,接受干预的卫生中心与对照组之间没有显著差异。在实验阶段,随机选择了 797 名参与者接受多组分干预。实施前进行的调整多变量分析显示,实验组和对照组之间的抑郁症没有显著差异。然而,干预后,观察到适度但显著的差异,这些差异在干预后 1 年仍然存在。
针对初级保健中管理抑郁症的临床指南实施的多组分干预措施可改善抑郁症的识别和记录的严重程度。