Christensen M, Foltved H, Rødbro P
Dan Med Bull. 1986 Aug;33(4):205-7.
A seven-class classification system for liver scintigraphy was developed to find or exclude metastases in a clinically defined population with gastrointestinal tumours. Scintigraphy was performed twice in fifty patients a few days apart. During a period of three years each scintigraphy was classified thrice as a consensus between two experienced observers at six occasions placed on three separate days. No substantial change in classification was seen whether the same scintigraphy was interpreted twice in a day or three years apart, although considerable uncertainty was seen in interpretation of near-normal scintigraphies. In dual scintigraphies, a significant lower reproducibility was noted--directly visualized in 10 percent of the patients--indicating that a recorded difference does not necessarily reflect a change in patient situation. We think the applied procedure may be valuable for evaluation of any imaging system for clinical use.
为了在临床定义的胃肠道肿瘤人群中发现或排除转移灶，开发了一种用于肝脏闪烁扫描的七类分类系统。对50名患者进行了两次闪烁扫描，间隔几天。在三年期间，每次闪烁扫描由两名经验丰富的观察者在三个不同日期的六次会诊中进行三次分类，作为共识。无论同一次闪烁扫描是在一天内解读两次还是相隔三年解读，分类都没有实质性变化，尽管在解读接近正常的闪烁扫描时存在相当大的不确定性。在双重闪烁扫描中，发现重现性显著降低——在10%的患者中可直接观察到——这表明记录的差异不一定反映患者病情的变化。我们认为所应用的程序可能对评估任何临床使用的成像系统有价值。
