Gross G, Roussaki A, Ikenberg H, Drees N
Dtsch Med Wochenschr. 1986 Sep 5;111(36):1351-5. doi: 10.1055/s-2008-1068633.
Persistent condylomata acuminata in a 21-year-old patient with diabetes mellitus were treated with highly purified interferon-alpha (IFN-alpha) obtained by recombinant DNA technology. Daily dose was 1.5 X 10(6) IU, given subcutaneously. Already during treatment the condylomata regressed. Two weeks after the end of therapy, i.e. after a total dose of 10.5 X 10(6) IU IFN-alpha, all condylomata had completely receded. Blood glucose levels remained constant with concomitant insulin therapy. Toxic side-effects or antibodies to IFN-alpha were not observed.
一名21岁的糖尿病患者的持续性尖锐湿疣，采用通过重组DNA技术获得的高纯度α干扰素（IFN-α）进行治疗。每日剂量为1.5×10⁶国际单位，皮下注射。治疗期间疣体即开始消退。治疗结束两周后，即给予总量10.5×10⁶国际单位IFN-α后，所有疣体已完全消退。同时进行胰岛素治疗，血糖水平保持稳定。未观察到毒性副作用或抗IFN-α抗体。
