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对于雷克斯分流术失败的患者,再次进行雷克斯分流术是更好的选择吗?

Is re-Rex shunt a better choice for patients with failed Rex shunt?

作者信息

Wen Zhe, Wang Jieqin, Yang Chao, Liu Tao, Liang Qifeng, Liang Jiankun, Ning Yu, You Fuyu, Bai Xiaoling, Hong Miao

机构信息

Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou Medical University, Guangzhou, China.

Clinical Data Center, Guangzhou Women and Children's Medical Center, Guangdong Provincial Clinical Research Center for Child Health, Institute of Pediatrics, Guangzhou Medical University, Guangzhou, China.

出版信息

Front Pediatr. 2023 Jun 26;11:1135059. doi: 10.3389/fped.2023.1135059. eCollection 2023.

Abstract

PURPOSE

To review our single-center surgical outcomes of redo operations after failed Rex shunt procedures.

METHODS

From September 2017 to October 2021, a total of 20 patients (11 males, 9 females; median age: 8.6 years) with Rex shunt occlusions were admitted to our hospital. Two of these patients were previously operated on in our hospital, and the remaining 18 were from other centers. All patients underwent repeat operations after detailed preoperative evaluations.

RESULTS

Preoperative wedged hepatic vein portography (WHVP) was conducted for 18 patients. Thirteen patients exhibited well-developed Rex recessus and intrahepatic portal vein during WHPV examination, consistent with the intraoperative exploration results. Fifteen patients (75%, 15/20) underwent redo-Rex shunt, four underwent Warren shunt and one underwent devascularization surgery. During the redo-Rex shunt operations, the left internal jugular veins (IJV) were used as bypass grafts in 11 patients; the intra-abdominal veins were used in 4 patients. The patients were followed up for 12-59 months (mean, 24.8 months). After redo Rex shunts, the grafts were patent in 14 patients (93.3%, 14/15), but 1 graft had thrombosis (6.7%, 1/15). Three patients suffered from postoperative anastomotic stenosis, and all of the stenosis was relieved with balloon dilatations. After re-Rex shunts, esophageal varices and spleen size were substantially reduced, and the platelet count significantly increased. Postoperative graft thrombosis was found in 1 patient after Warren shunt (1/4, 25%), and there was no graft stenosis. Compared with Warren surgery, patients who underwent re-Rex shunt had a significantly higher rate of platelet increase.

CONCLUSIONS

Redo-rex shunts can be finished in most patients with failed Rex shunts. Re-Rex shunt is a preferred surgical choice after a failed Rex shunt when a good bypass graft is available, and the surgical success rate can reach more than 90%. A suitable bypass graft is essential for a successful redo Rex shunt. Preoperative WHVP is recommended for the design of a redo surgical plan preoperatively.

摘要

目的

回顾我们单中心Rex分流术失败后再次手术的结果。

方法

2017年9月至2021年10月,共有20例(11例男性,9例女性;中位年龄:8.6岁)Rex分流术闭塞患者入住我院。其中2例患者曾在我院接受手术,其余18例来自其他中心。所有患者在详细的术前评估后均接受了再次手术。

结果

对18例患者进行了术前肝静脉楔入造影(WHVP)。13例患者在WHPV检查时显示Rex隐窝和肝内门静脉发育良好,与术中探查结果一致。15例患者(75%,15/20)接受了再次Rex分流术,4例接受了Warren分流术,1例接受了去血管化手术。在再次Rex分流术中,11例患者使用左颈内静脉(IJV)作为旁路移植物;4例患者使用腹内静脉。患者随访12 - 59个月(平均24.8个月)。再次Rex分流术后,14例患者(93.3%,14/15)的移植物通畅,但1例移植物发生血栓形成(6.7%,1/15)。3例患者出现术后吻合口狭窄,所有狭窄均通过球囊扩张得到缓解。再次Rex分流术后,食管静脉曲张和脾脏大小显著减小,血小板计数显著增加。1例接受Warren分流术的患者术后出现移植物血栓形成(1/4,25%),未出现移植物狭窄。与Warren手术相比,接受再次Rex分流术的患者血小板升高率显著更高。

结论

大多数Rex分流术失败的患者可以完成再次Rex分流术。当有合适的旁路移植物时,再次Rex分流术是Rex分流术失败后的首选手术方式,手术成功率可达90%以上。合适的旁路移植物对于再次Rex分流术的成功至关重要。建议术前进行WHVP以设计再次手术方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d11/10331016/d28e8d39350b/fped-11-1135059-g001.jpg

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