Suppr超能文献

保罗青光眼植入物用于儿童青光眼的早期经验:病例系列

Early Experience with the Paul Glaucoma Implant in Childhood Glaucoma: A Case Series.

作者信息

Elhusseiny Abdelrahman M, Khodeiry Mohamed M, Lee Richard K, Shaarawy Tarek, Waqar Salman, Sayed Mohamed S

机构信息

Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Department of Ophthalmology, Boston Children's Hospital, Boston, MA, USA.

出版信息

Clin Ophthalmol. 2023 Jul 6;17:1939-1944. doi: 10.2147/OPTH.S414183. eCollection 2023.

Abstract

PURPOSE

The Paul glaucoma implant (PGI, Advanced Ophthalmic Innovations, Singapore, Republic of Singapore) is a recently developed novel non-valved glaucoma drainage device (GDD) designed to effectively reduce the intraocular pressure (IOP) in glaucoma patients with a theoretically reduced risk of postoperative complications such as hypotony, endothelial cell loss, strabismus, and diplopia. Limited literature has evaluated its use in adult glaucoma; however, its use in pediatric glaucoma has not been reported to date. We present our early experience with PGI in refractory childhood glaucoma.

PATIENTS AND METHODS

This study was retrospective single-surgeon case series in a single tertiary center.

RESULTS

Three eyes of 3 patients with childhood glaucoma were enrolled in the study. During nine months of follow-up, postoperative IOP and number of glaucoma medications were significantly lower than preoperative values in all the enrolled patients. None of the patients developed postoperative complications including postoperative hypotony, choroidal detachment, endophthalmitis, or corneal decompensation.

CONCLUSION

PGI is an efficient and relatively safe surgical treatment option in patients with refractory childhood glaucoma. Further studies with larger number of participants and longer follow-up period are required to confirm our encouraging results.

摘要

目的

保罗青光眼植入物(PGI,新加坡先进眼科创新公司)是一种最近研发的新型无阀青光眼引流装置(GDD),旨在有效降低青光眼患者的眼压(IOP),理论上可降低术后并发症如低眼压、内皮细胞丢失、斜视和复视的风险。仅有有限的文献评估了其在成人青光眼中的应用;然而,迄今为止尚未有其在儿童青光眼中应用的报道。我们介绍我们在难治性儿童青光眼中使用PGI的早期经验。

患者与方法

本研究是在单一三级中心进行的回顾性单术者病例系列研究。

结果

3例儿童青光眼患者的3只眼纳入研究。在9个月的随访期间,所有纳入患者术后的眼压和青光眼药物使用数量均显著低于术前值。所有患者均未发生术后并发症,包括术后低眼压、脉络膜脱离、眼内炎或角膜失代偿。

结论

PGI是难治性儿童青光眼患者一种有效且相对安全的手术治疗选择。需要开展更多参与者和更长随访期的进一步研究来证实我们令人鼓舞的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ec/10332410/9227797fe345/OPTH-17-1939-g0001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验