Department of Medicine, Section of Gastroenterology, Boston University School of Medicine, Boston, MA.
Department of Medicine, Section of Gastroenterology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
J Clin Gastroenterol. 2023 Oct 1;57(9):855-862. doi: 10.1097/MCG.0000000000001893.
Colorectal cancer (CRC) is a leading cause of morbidity and mortality worldwide and its incidence increases with age. The proportion of older adults in the United States continues to rise, making CRC prevention a key health priority for our aging population. CRC is a largely preventable disease through screening and polyp surveillance, and noninvasive modalities represent an important option for older adults in whom the burdens and risks of invasive testing are higher compared with younger adults. This review highlights the evidence, risks, and benefits of noninvasive CRC screening and surveillance options in older adults and discusses the challenges of CRC prevention in this cohort.
结直肠癌（CRC）是全球发病率和死亡率的主要原因，其发病率随着年龄的增长而增加。美国老年人的比例不断上升，使 CRC 的预防成为我们老龄化人口的一个主要健康重点。CRC 是一种主要通过筛查和息肉监测来预防的疾病，非侵入性方法是年龄较大的成年人的重要选择，与年轻人相比，侵入性检测的负担和风险更高。本综述重点介绍了非侵入性 CRC 筛查和监测方法在老年人中的证据、风险和益处，并讨论了在这一年龄组中预防 CRC 的挑战。
