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使用AirSeal®系统与标准气腹机进行腹腔镜部分肾切除术的比较:来自一家转诊中心的结果

Comparison of laparoscopic partial nephrectomy performed with AirSeal® system vs. standard insufflator: results from a referral center.

作者信息

Forte Flavio, Tripodi Domenico, Pironi Daniele, Corongiu Emanuele, Gagliardi Federica, Frisenda Marco, Gallo Gaetano, Quarantiello Antonia, Di Lorenzo Giuseppe, Cavaleri Yuri, Salciccia Stefano, Lori Eleonora, Sorrenti Salvatore

机构信息

Department of Urology, M.G. Vannini Hospital, Rome, Italy.

Department of Surgery, Sapienza University of Rome, Rome, Italy.

出版信息

Front Surg. 2023 Jun 27;10:1220332. doi: 10.3389/fsurg.2023.1220332. eCollection 2023.

DOI:10.3389/fsurg.2023.1220332
PMID:37440928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10335758/
Abstract

OBJECTIVE

To compare perioperative and oncologic surgical outcomes during laparoscopic partial nephrectomy (LPN) performed by standard carbon dioxide insufflation, with those from surgeries in which the AirSeal® intelligent insufflation system was used for renal tumors.

MATERIALS AND METHODS

A total of 27 patients with renal tumor were identified, 14 underwent LPN with AirSeal® (group A) and 13 LPN with standard insufflator (group B), respectively. Demographic baseline characteristics were similar in the two groups.

RESULTS

The size of the tumor was largest in group B (29.64 vs. 32.1 mm). The mean operative time was shorter in the AirSeal® group [group A: mean 109.0 min, median 107.5 min, interquartile range (IQR) 85; group B: mean 121.0 min, median 120.0 min, IQR 50.0]. Positive margin rates were absent in the two groups. Estimated blood loss presented a difference in the perioperative period (group A: mean 1.5 g/dL, median 1.45 g/dL; group B: mean 2.15 g/dL, median 2.2 g/dL). Time to ischemia was found to be shorter in group A with a median of 18 min compared to a median of 20 min in group B. No subcutaneous emphysema, pneumothorax, and pneumomediastinum cases occurred in either group. A postoperative complication developed in one patient requiring superselective embolization.

CONCLUSION

In selected patients, our preliminary surgical experience has shown that the LPN procedure performed with the aid of the AirSeal® intelligent insufflation system can be used to treat even medium-/high-complexity kidney lesions, with a reduction in operating times, lower rates of complications, and perioperative blood loss.

CLINICAL TRIAL REGISTRATION

AirSealV1.

摘要

目的

比较采用标准二氧化碳气腹法进行腹腔镜肾部分切除术(LPN)时的围手术期和肿瘤手术结果,与使用AirSeal®智能气腹系统进行肾肿瘤手术的结果。

材料与方法

共纳入27例肾肿瘤患者,其中14例行使用AirSeal®的LPN(A组),13例行使用标准气腹机的LPN(B组)。两组的人口统计学基线特征相似。

结果

B组肿瘤最大径更大(29.64对32.1 mm)。AirSeal®组的平均手术时间更短[A组:平均109.0 分钟,中位数107.5分钟,四分位数间距(IQR)85;B组:平均121.0分钟,中位数120.0分钟,IQR 50.0]。两组均无切缘阳性率。围手术期估计失血量存在差异(A组:平均1.5 g/dL,中位数1.45 g/dL;B组:平均2.15 g/dL,中位数2.2 g/dL)。发现A组的缺血时间更短,中位数为18分钟,而B组中位数为20分钟。两组均未发生皮下气肿、气胸和纵隔气肿病例。1例患者出现术后并发症,需要进行超选择性栓塞。

结论

在选定患者中,我们的初步手术经验表明,借助AirSeal®智能气腹系统进行的LPN手术可用于治疗甚至中/高复杂性肾病变,同时可缩短手术时间、降低并发症发生率和减少围手术期失血量。

临床试验注册

AirSealV1 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/955f/10335758/a3f0dfc2c453/fsurg-10-1220332-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/955f/10335758/a3f0dfc2c453/fsurg-10-1220332-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/955f/10335758/a3f0dfc2c453/fsurg-10-1220332-g001.jpg

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