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Strategies to improve γδTCRs engineered T-cell therapies for the treatment of solid malignancies.

作者信息

Meringa A D, Hernández-López P, Cleven A, de Witte M, Straetemans T, Kuball J, Beringer D X, Sebestyen Z

机构信息

Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

Department of Hematology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

出版信息

Front Immunol. 2023 Jun 27;14:1159337. doi: 10.3389/fimmu.2023.1159337. eCollection 2023.

DOI:10.3389/fimmu.2023.1159337
PMID:37441064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10333927/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/382e/10333927/1aaf45b4e7f8/fimmu-14-1159337-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/382e/10333927/1aaf45b4e7f8/fimmu-14-1159337-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/382e/10333927/1aaf45b4e7f8/fimmu-14-1159337-g001.jpg

相似文献

[1]
Strategies to improve γδTCRs engineered T-cell therapies for the treatment of solid malignancies.

Front Immunol. 2023-6-27

[2]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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引用本文的文献

[1]
γδT cells, a key subset of T cell for cancer immunotherapy.

Front Immunol. 2025-3-28

[2]
Rational Design and Organoid-Based Evaluation of a Cocktail CAR-γδ T Cell Therapy for Heterogeneous Glioblastoma.

Adv Sci (Weinh). 2025-5

本文引用的文献

[1]
Exhausted intratumoral Vδ2 γδ T cells in human kidney cancer retain effector function.

Nat Immunol. 2023-4

[2]
γδ T cells are effectors of immunotherapy in cancers with HLA class I defects.

Nature. 2023-1

[3]
The emerging roles of γδ T cells in cancer immunotherapy.

Nat Rev Clin Oncol. 2023-3

[4]
Four challenges to CAR T cells breaking the glass ceiling.

Eur J Immunol. 2023-11

[5]
Cytotoxic activity of anti-mucin 1 chimeric antigen receptor T cells expressing PD-1-CD28 switch receptor against cholangiocarcinoma cells.

Cytotherapy. 2023-2

[6]
Chemokine switch regulated by TGF-β1 in cancer-associated fibroblast subsets determines the efficacy of chemo-immunotherapy.

Oncoimmunology. 2022

[7]
Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint.

EBioMedicine. 2022-9

[8]
Engineering Next-Generation CAR-T Cells: Overcoming Tumor Hypoxia and Metabolism.

Annu Rev Chem Biomol Eng. 2022-6-10

[9]
Exhaustion of CAR T cells: potential causes and solutions.

J Transl Med. 2022-5-23

[10]
Improving CAR-T immunotherapy: Overcoming the challenges of T cell exhaustion.

EBioMedicine. 2022-3

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