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粪嵌塞与非穿孔性粪性结肠炎:不良结局的警示信号

Fecal Impaction and Nonperforated Stercoral Colitis: Red Flags for Poor Outcomes.

作者信息

Sacerdote Michael, Limback Joseph, Zhu Jianbin

机构信息

Radiology, AdventHealth Orlando, Orlando, USA.

Biostatistics, AdventHealth Orlando, Orlando, USA.

出版信息

Cureus. 2023 Jul 11;15(7):e41705. doi: 10.7759/cureus.41705. eCollection 2023 Jul.

Abstract

Fecal impaction and stercoral colitis are common, yet little research has been performed on the associated mortality risk. We performed a retrospective cohort study of 970 hospital encounters representing 885 unique patients in which fecal impaction or stercoral colitis was identified in CT reports. Among the 535 patients with fecal impaction, 13.3% died or were discharged to hospice, compared to 13.1% among the 428 patients with nonperforated stercoral colitis (p = 0.93). Of the seven patients with perforation, five died or were discharged to hospice. The risk of death or discharge to hospice for patients with fecal impaction or nonperforated stercoral colitis aged 18-49 was 2.9% and rose approximately 4% each decade thereafter to 21.9% for patients 90 and older (p< 0.001). Patients with a body mass index of 25-30 had an 8.1% risk of death or discharge to hospice, compared to 23.4% for those with a BMI < 18.5 (p< 0.001). Patients with at least one ICD-10 code for dementia, paralysis/neuromuscular disease, or malnutrition/failure to thrive had a risk of death or discharge to hospice of 21.6%, compared to 1.9% among patients with none of these risk factors (p< 0.001). ICD-10 codes for sepsis were associated with 90.0% of the deaths and 44.3% of the discharges to hospice. Patients diagnosed in less than three hours had a risk of death or discharge to hospice of 8.0%, compared to a risk of 20.1% for those diagnosed in ≥ 12 hours (p< 0.001).

摘要

粪块嵌塞和粪性结肠炎很常见,但关于其相关死亡风险的研究却很少。我们对970例住院病例进行了一项回顾性队列研究,这些病例代表了885名独特的患者,CT报告中发现了粪块嵌塞或粪性结肠炎。在535例粪块嵌塞患者中,13.3%死亡或出院后进入临终关怀机构,相比之下,428例非穿孔性粪性结肠炎患者中的这一比例为13.1%(p = 0.93)。在7例穿孔患者中,5例死亡或出院后进入临终关怀机构。18至49岁的粪块嵌塞或非穿孔性粪性结肠炎患者死亡或出院后进入临终关怀机构的风险为2.9%,此后每十年增加约4%,90岁及以上患者的这一风险为21.9%(p<0.001)。体重指数为25至30的患者死亡或出院后进入临终关怀机构的风险为8.1%,而体重指数<18.5的患者这一风险为23.4%(p<0.001)。至少有一个痴呆、瘫痪/神经肌肉疾病或营养不良/发育不良的ICD-10编码的患者死亡或出院后进入临终关怀机构的风险为21.6%,而没有这些风险因素的患者这一风险为1.9%(p<0.001)。脓毒症的ICD-10编码与90.0%的死亡病例和44.3%的出院后进入临终关怀机构的病例相关。诊断时间少于三小时的患者死亡或出院后进入临终关怀机构的风险为8.0%,而诊断时间≥12小时的患者这一风险为20.1%(p<0.001)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/10335362/1917fe0b1b1d/cureus-0015-00000041705-i01.jpg

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