Kim Hyangkyoung, Kwon Tae-Won, Cho Yong-Pil, Gwon Jun Gyo, Han Youngjin, Lee Sang Ah, Kim Ye-Jee, Kim Seonok
Department of Surgery, Ewha Womans University College of Medicine, Seoul, Korea.
Division of Vascular Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Ann Surg Treat Res. 2023 Jul;105(1):37-46. doi: 10.4174/astr.2023.105.1.37. Epub 2023 Jul 4.
Although endovascular aneurysm repair (EVAR) has been shown to be superior to open surgical repair (OSR) for abdominal aortic aneurysm (AAA) treatment, no large-scale studies in the Korean population have compared outcomes and costs.
The National Health Insurance Service database in Korea was screened to identify AAA patients treated with EVAR or OSR from 2008 to 2019. Perioperative, early postoperative, and long-term survival were compared, as were reinterventions and complications. Patients were followed-up through 2020.
Of the 13,631 patients identified, 2,935 underwent OSR and 10,696 underwent EVAR. Perioperative mortality rate was lower in the EVAR group (4.2% 8.0%, P < 0.001) even after excluding patients with ruptured AAA (2.7% 3.3%, P = 0.003). However, long-term mortality rate per 100 person-years was significantly higher in the EVAR than in the OSR group (9.0 6.4, P < 0.001), and all-cause mortality was lower in the OSR group (hazard ratio, 0.9; 95% confidence interval, 0.87-0.97, P = 0.008). EVAR had a higher AAA-related reintervention rate per 100 person-years (1.75 0.52), and AAA-related reintervention costs were almost 10-fold higher with EVAR (US dollar [USD] 6,153,463) than with OSR (USD 624,216).
While EVAR may have short-term advantages, OSR may provide better long-term outcomes and cost-effectiveness for AAA treatment in the Korean population, under the medical expense system in Korea.
尽管血管内动脉瘤修复术(EVAR)已被证明在治疗腹主动脉瘤(AAA)方面优于开放手术修复(OSR),但在韩国人群中尚未有大规模研究比较两者的疗效和成本。
对韩国国民健康保险服务数据库进行筛查,以确定2008年至2019年期间接受EVAR或OSR治疗的AAA患者。比较围手术期、术后早期和长期生存率,以及再次干预和并发症情况。对患者随访至2020年。
在13631例确诊患者中,2935例行OSR,10696例行EVAR。即使排除AAA破裂患者,EVAR组围手术期死亡率仍较低(4.2%对8.0%,P<0.001)(2.7%对3.3%,P=0.003)。然而,EVAR组每100人年的长期死亡率显著高于OSR组(9.0对6.4,P<0.001),OSR组全因死亡率较低(风险比,0.9;95%置信区间,0.87-0.97,P=0.008)。EVAR每100人年的AAA相关再次干预率较高(1.75对0.52),且EVAR的AAA相关再次干预成本几乎是OSR的10倍(6153463美元)(624216美元)。
在韩国的医疗费用体系下,虽然EVAR可能有短期优势,但OSR在治疗韩国人群的AAA方面可能提供更好的长期疗效和成本效益。