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基于人群的腹主动脉瘤破裂研究。

Population-based study of ruptured abdominal aortic aneurysm.

机构信息

Department of Vascular Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

出版信息

Br J Surg. 2016 Nov;103(12):1634-1639. doi: 10.1002/bjs.10200. Epub 2016 Aug 10.

DOI:10.1002/bjs.10200
PMID:27508946
Abstract

BACKGROUND

The incidence of abdominal aortic aneurysms (AAAs) and their rupture has been reported to be decreasing. The aim was to evaluate trends in ruptured AAA (rAAA) incidence in the hospital district of Helsinki and Uusimaa (HUS) in southern Finland. This was a population-based retrospective review of all patients with rAAA in this well defined geographical area during 2003-2013.

METHODS

Data for all patients treated for rAAA at Helsinki University Hospital, the only vascular surgery centre in an area of 1·5 million inhabitants, were collected from local vascular registry. All deaths attributed to rAAA were obtained from the cause of death registry of Statistics Finland.

RESULTS

The mean(s.d.) age of the 712 patients with rAAA was 76·5(9·6) years; 76·7 per cent of them were men. Only 330 patients (46·3 per cent of those with rAAA) arrived alive at Helsinki University Hospital. The turn-down rate for surgical treatment was 10·3 per cent. Of the 296 patients operated on, 199 (67·2 per cent) were alive at 30 days. Only 27·9 per cent of all patients were alive 30 days after rupture of the AAA. The incidence of rAAA was 4·3 per 100 000 inhabitants and the mortality rate was 3·2 per 100 000 inhabitants. A decreasing trend was seen in incidence and mortality during the 11-year study interval.

CONCLUSION

The incidence of rAAA is decreasing in the HUS district. Mortality from rAAA remains very high, because half of the patients die before reaching the hospital.

摘要

背景

腹主动脉瘤(AAA)的发病率及其破裂率据报道呈下降趋势。本研究旨在评估芬兰南部赫尔辛基和乌西玛大区(HUS)医院区破裂性腹主动脉瘤(rAAA)的发病率趋势。这是一项针对该特定地理区域内所有 rAAA 患者的基于人群的回顾性研究,研究时间为 2003 年至 2013 年。

方法

赫尔辛基大学医院(该地区唯一的血管外科中心,服务人口为 150 万)所有 rAAA 患者的治疗数据均从当地血管登记处收集。所有归因于 rAAA 的死亡均从芬兰统计局的死因登记处获得。

结果

712 例 rAAA 患者的平均(标准差)年龄为 76.5(9.6)岁;76.7%为男性。仅有 330 例(rAAA 患者的 46.3%)存活到达赫尔辛基大学医院。手术治疗的拒诊率为 10.3%。296 例接受手术的患者中,199 例(67.2%)在 30 天内存活。AAA 破裂后 30 天,所有患者中仅有 27.9%存活。rAAA 的发病率为每 10 万人 4.3 例,死亡率为每 10 万人 3.2 例。在 11 年的研究期间,发病率和死亡率呈下降趋势。

结论

HUS 区 rAAA 的发病率正在下降。rAAA 的死亡率仍然很高,因为一半的患者在到达医院之前就已死亡。

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