Department of General Surgery/Shanghai Clinical Nutrition Research Center, Zhongshan Hospital, Fudan University, Shanghai, China.
School of Medicine and Surgery, University of Milano-Bicocca, and HBP Surgery Unit, and Foundation IRCCS San Gerardo, Monza, Italy.
Nutrition. 2023 Oct;114:112132. doi: 10.1016/j.nut.2023.112132. Epub 2023 Jun 14.
Wasting in cancer patients has long been recognized as a condition that adversely affects cancer patients' quality of life, treatment tolerance, and oncological outcomes. Historically, this condition was mainly evaluated by changes in body weight. However, this approach is not quite accurate because body weight is the overall change of all body compartments. Conditions such as edema and ascites can mask the severity of muscle and adipose tissue depletion. Changes in body composition assessment in cancer patients have historically been underappreciated because of the limited availability of measurement tools. As more evidence highlighting the importance of body composition has emerged, it is imperative to apply a more precise evaluation of nutritional status and a more targeted approach to provide nutritional support for cancer patients. In this review, we will discuss the modalities for evaluating body composition and how to manage body composition changes in cancer patients.
癌症患者的消瘦问题一直以来都被认为是一种会对患者的生活质量、治疗耐受性和肿瘤预后产生不良影响的情况。从历史上看，这种情况主要通过体重变化来评估。然而，这种方法并不十分准确，因为体重是所有身体部位的总体变化。水肿和腹水等情况可能会掩盖肌肉和脂肪组织消耗的严重程度。由于测量工具的缺乏，癌症患者的身体成分评估在历史上一直被低估。随着越来越多的证据强调身体成分的重要性，有必要更精确地评估营养状况，并采取更有针对性的方法为癌症患者提供营养支持。在这篇综述中，我们将讨论评估身体成分的方法以及如何管理癌症患者的身体成分变化。
