Li Yang, Yan Zhihong, Fan Jiahua, Yao Xuelian, Cai Ying
College of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, 330004, China.
College of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, 330004, China.
Talanta. 2023 Dec 1;265:124916. doi: 10.1016/j.talanta.2023.124916. Epub 2023 Jul 6.
Covalent organic framework coated nickel foam (NF@COF) was prepared as a sorbent for the dispersive solid phase extraction (DSPE) of polycyclic aromatic hydrocarbons (PAHs) from Chinese herbal medicines (CHMs) prior to their determination by gas chromatography-mass spectrometry (GC-MS). The structure and morphology of the as-synthesized NF@COF were characterized by different techniques. Various key parameters affecting the performance of the DSPE method, including the amount of sorbent, desorption solvent, desorption volume and time, extraction time, and sample volume, were investigated. Under the optimized conditions, NF@COF combined with GC-MS was successfully applied to the determination of 16 PAHs in CHMs. The method showed wide linearity (20-2000 ng mL), low limits of determination (0.3-2.7 ng mL), and high recoveries (78.0-124%). These results revealed that NF@COF has the potential for efficient extraction of PAHs from complex samples.
制备了共价有机框架包覆泡沫镍（NF@COF），作为一种吸附剂，用于在采用气相色谱 - 质谱联用（GC - MS）测定之前，对中药材中的多环芳烃（PAHs）进行分散固相萃取（DSPE）。采用不同技术对合成的NF@COF的结构和形貌进行了表征。研究了影响DSPE方法性能的各种关键参数，包括吸附剂用量、解吸溶剂、解吸体积和时间、萃取时间以及样品体积。在优化条件下，NF@COF与GC - MS联用成功应用于中药材中16种PAHs的测定。该方法线性范围宽（20 - 2000 ng mL）、测定下限低（0.3 - 2.7 ng mL）且回收率高（78.0 - 124%）。这些结果表明，NF@COF具有从复杂样品中高效萃取PAHs的潜力。
