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前节光学相干断层扫描在翼状胬肉评估中的作用。

The role of anterior segment optical coherence tomography in the evaluation of the pterygium.

机构信息

Medical Faculty Department of Ophthalmology, Yuzuncu Yıl University, Goz Hastaliklari AD, Van 65080, Turkey.

Medical Faculty Department of Ophthalmology, Yeni Yuzyil University, Istanbul, Turkey.

出版信息

Photodiagnosis Photodyn Ther. 2023 Sep;43:103704. doi: 10.1016/j.pdpdt.2023.103704. Epub 2023 Jul 11.

DOI:10.1016/j.pdpdt.2023.103704
PMID:37442409
Abstract

BACKGROUND

To evaluate the ability of anterior segment optical coherence tomography (AS-OCT) to visualize the anatomic features of the pterygium and its invasion of the corneal layers.

METHODS

Seventy-five eyes of 54 patients diagnosed with pterygium were included. All subjects underwent complete ophthalmologic examinations, including AS-OCT. The limbus-apex distance, vertical height at the limbus, invasion of the Bowman's and stromal layers, and other morphologic structures of the pterygium tissue were analyzed.

RESULTS

The mean age of the patients was 49.67 ± 16.49 (20-85) years. The mean apex-limbus distance was 2548.37 ± 1026.32 (933-4597) μm, and the mean vertical height at the limbus was 4843.89 ± 1374.10 (1740-7784) μm. A space was observed beneath the pterygium tissue in 44 (58.67%) eyes. The mean width and height of this space were 1756.33 ± 560.22 (1009-3095) μm and 231.70 ± 85.88 (109-465) μm, respectively. Invasion of the Bowman's layer was apparent in 74 (98.67%) eyes, and invasion of the stromal layer was detected in 33 (44%) eyes. A hyperreflective layer was observed beneath the epithelial layer at the edge of the pterygium apex in 31 (41.33%) eyes. In 24 (92.31%) of the 26 advanced pterygium cases and 20 (40.82%) of the 49 early pterygium cases, a subpterygium space was found beneath the lesion (p = 0.0001).

CONCLUSION

AS-OCT enables measurement of the actual size and thickness of pterygia, assessment of invasion of the Bowman's and stromal layers of the cornea, and evaluation of the pterygium structure. Over half of the eyes exhibited space beneath the pterygium.

摘要

背景

评估眼前节光学相干断层扫描(AS-OCT)观察翼状胬肉解剖特征及其对角膜各层侵袭的能力。

方法

纳入 54 例(75 只眼)诊断为翼状胬肉的患者。所有患者均接受全面眼科检查,包括 AS-OCT。分析翼状胬肉体组织的角膜缘-顶点距离、角膜缘垂直高度、侵犯Bowman 层和基质层情况以及其他形态结构。

结果

患者平均年龄为 49.67±16.49(20-85)岁。平均角膜缘-顶点距离为 2548.37±1026.32(933-4597)μm,平均角膜缘垂直高度为 4843.89±1374.10(1740-7784)μm。44 只(58.67%)眼的翼状胬肉体组织下可见一空间。该空间的平均宽度和高度分别为 1756.33±560.22(1009-3095)μm 和 231.70±85.88(109-465)μm。74 只(98.67%)眼可见侵犯 Bowman 层,33 只(44%)眼可见侵犯基质层。31 只(41.33%)眼翼状胬肉顶点处上皮层边缘可见一高反射层。26 例进展期翼状胬肉中有 24 例(92.31%)和 49 例早期翼状胬肉中有 20 例(40.82%)病变下方存在亚翼状胬肉体(p=0.0001)。

结论

AS-OCT 可用于测量翼状胬肉的实际大小和厚度,评估对角膜 Bowman 层和基质层的侵犯程度,评价翼状胬肉的结构。超过一半的眼可见翼状胬肉体下有空腔。

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