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氧化平衡评分与睡眠质量的关系:NHANES 2007-2014。

Association of oxidative balance score with sleep quality: NHANES 2007-2014.

机构信息

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

出版信息

J Affect Disord. 2023 Oct 15;339:435-442. doi: 10.1016/j.jad.2023.07.040. Epub 2023 Jul 11.

Abstract

BACKGROUND

Oxidative stress is correlated with sleep quality. A common tool for evaluating dietary and lifestyle exposures to oxidative stress is the Oxidative Balance Score (OBS), with higher OBS suggesting more substantial antioxidant exposures. The relationship between OBS and sleep quality is unclear. Investigating the association between OBS and sleep quality was the purpose of this study.

METHODS

To figure out the relationship between OBS and sleep quality, we utilized weighted linear models and weighted logistic regression. Adjusted models were also examined.

RESULTS

6300 participants who took part in the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2014 were recruited. OBS was negatively associated with sleep disorder (OR: 0.97; 95 % CI: 0.94-0.99), and positively associated with sleep duration (MD: 0.02; 95%CI: 0.01-0.03). Within the range of OBS > 24, each unit increase in OBS will result in a 40 % reduction in sleep disorder, and a 26 % increasement in sleep duration after adjustment (all P for trend <0.05). Dietary and lifestyle components were closely related to sleep quality independently. The relationship between OBS and sleep quality was prominent in the female population under 50 years of age. After stratification by education level, this relationship persisted.

LIMITATION

This research was cross-sectional design, and it was not possible to deduce causality.

CONCLUSION

Diet and lifestyle might influence sleep quality by modulating oxidative balance. Antioxidant diets and lifestyles were important in reducing sleep problems and our study also provided new ideas for improving sleep quality.

摘要

背景

氧化应激与睡眠质量有关。评估饮食和生活方式对氧化应激暴露的常用工具是氧化平衡评分(OBS),OBS 越高表示抗氧化暴露越充分。OBS 与睡眠质量之间的关系尚不清楚。本研究旨在探讨 OBS 与睡眠质量之间的关系。

方法

为了研究 OBS 与睡眠质量之间的关系,我们使用了加权线性模型和加权逻辑回归。还检查了调整后的模型。

结果

共纳入了 6300 名参加 2007 年至 2014 年国家健康与营养调查(NHANES)的参与者。OBS 与睡眠障碍呈负相关(OR:0.97;95%CI:0.94-0.99),与睡眠时间呈正相关(MD:0.02;95%CI:0.01-0.03)。在 OBS>24 的范围内,OBS 每增加一个单位,睡眠障碍的发生率就会降低 40%,调整后睡眠时间增加 26%(所有趋势 P<0.05)。饮食和生活方式因素与睡眠质量独立相关。OBS 与睡眠质量之间的关系在 50 岁以下的女性人群中更为明显。按教育程度分层后,这种关系仍然存在。

局限性

本研究为横断面设计,无法推断因果关系。

结论

饮食和生活方式可能通过调节氧化平衡影响睡眠质量。抗氧化饮食和生活方式对于减少睡眠问题很重要,本研究也为改善睡眠质量提供了新的思路。

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