颅内动脉瘤性蛛网膜下腔出血后的全身炎症反应。
Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage.
机构信息
Department of Medical Education, National Taiwan University, School of Medicine, Taipei 100, Taiwan.
Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital Yunlin Branch, Yunlin 640, Taiwan.
出版信息
Int J Mol Sci. 2023 Jun 30;24(13):10943. doi: 10.3390/ijms241310943.
Abstract
Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological disorders, with a high mortality rate and severe disabling functional sequelae. Systemic inflammation following hemorrhagic stroke may play an important role in mediating intracranial and extracranial tissue damage. Previous studies showed that various systemic inflammatory biomarkers might be useful in predicting clinical outcomes. Anti-inflammatory treatment might be a promising therapeutic approach for improving the prognosis of patients with aSAH. This review summarizes the complicated interactions between the nervous system and the immune system.
摘要
颅内动脉瘤性蛛网膜下腔出血（aSAH）是最严重的神经系统疾病之一，具有较高的死亡率和严重的致残性功能后遗症。出血性中风后的全身炎症可能在介导颅内和颅外组织损伤中起重要作用。先前的研究表明，各种全身性炎症生物标志物可能有助于预测临床结果。抗炎治疗可能是改善 aSAH 患者预后的一种有前途的治疗方法。本综述总结了神经系统和免疫系统之间复杂的相互作用。
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