Huang Sherri, Rodriguez Camilo, Shakfeh Khalid, Smith Jorden, Reddy Koushik
Internal Medicine and Pediatrics, University of South Florida Morsani College of Medicine, Tampa, USA.
Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, USA.
Cureus. 2023 Jun 12;15(6):e40314. doi: 10.7759/cureus.40314. eCollection 2023 Jun.
Patients undergoing procedures are often transitioned off anticoagulants using anti-platelet agents with short half-lives as a "bridge." We present the case of a patient with a history of in-stent thromboses who experienced a thrombotic event following a literature-guided bridging protocol. This case is one of the first to show that stopping cangrelor within six hours led to a need for urgent revascularization and suggests that the timing for discontinuing bridging agents should be customized based on the patient's history of increased blood clotting.
接受手术的患者通常会使用半衰期短的抗血小板药物作为“桥梁”，从抗凝药物过渡下来。我们报告了一例有支架内血栓形成病史的患者，该患者在遵循文献指导的桥接方案后发生了血栓事件。该病例是首批表明在六小时内停用坎格雷洛导致需要紧急血运重建的病例之一，并提示应根据患者血液凝固增加的病史来定制停用桥接药物的时机。
