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玫瑰单胞菌属菌血症伴发心内膜炎及可能的中枢神经系统脓毒性栓塞现象。

Roseomonas Species Bacteremia With Associated Endocarditis and Possible CNS Septic Embolic Phenomenon.

作者信息

Rodriguez Jose A, Gushiken Alexis C

机构信息

Infectious Diseases, University of Florida, Gainesville, USA.

Infectious Disease, University of Florida, Gainesville, USA.

出版信息

Cureus. 2023 Jun 12;15(6):e40318. doi: 10.7759/cureus.40318. eCollection 2023 Jun.

Abstract

species has been associated with infections in both immunocompetent and immunocompromised hosts, manifesting as peritonitis, bacteremia, catheter-related bacteremia, endophthalmitis, spondylitis, and endocarditis. Here we present a man in his 60s who was brought to our institution for sudden onset of aphasia, right-sided paresthesia, and new onset tonic-clonic seizure episodes. At presentation, he was found to have severe lactic acidosis, acute kidney failure, bilateral hydronephrosis, elevated prostate-specific antigen (PSA), and an enlarged prostate. Blood cultures obtained on admission later grew species for which he was started on meropenem. A trans-esophageal echocardiogram (TEE) showed multiple very thin mobile densities on the ventricular side of the aortic valve; magnetic resonance imaging (MRI) of the brain revealed an 11 mm acute/subacute hemorrhage. The patient was discharged in stable condition on Ertapenem intravenous therapy for six weeks. can be a cause of endocarditis. The antimicrobial resistance profile of  suggests that carbapenems, fluoroquinolones or aminoglycosides are the drugs of choice for Roseomonas infections and that infectious diseases involved in cases of infections should be instituted promptly for proper management.

摘要

该菌种已与免疫功能正常和免疫功能低下宿主的感染相关,表现为腹膜炎、菌血症、导管相关菌血症、眼内炎、脊柱炎和心内膜炎。在此,我们报告一名60多岁的男性,因突然出现失语、右侧感觉异常和新发强直阵挛性癫痫发作被送至我院。就诊时,发现他患有严重乳酸酸中毒、急性肾衰竭、双侧肾积水、前列腺特异性抗原(PSA)升高以及前列腺肿大。入院时采集的血培养后来培养出该菌种,为此他开始使用美罗培南治疗。经食管超声心动图(TEE)显示主动脉瓣心室侧有多个非常薄的活动密度影;脑部磁共振成像(MRI)显示有一个11毫米的急性/亚急性出血灶。患者接受厄他培南静脉治疗六周后病情稳定出院。该菌种可能是心内膜炎的病因。该菌种的抗菌药物耐药谱表明,碳青霉烯类、氟喹诺酮类或氨基糖苷类是玫瑰单胞菌感染的首选药物,对于玫瑰单胞菌感染病例所涉及的传染病应及时进行妥善管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1a/10337875/63844aeceba1/cureus-0015-00000040318-i01.jpg

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