Quacinella Michael A, Yong Taylor M, Obremskey William T, Stinner Daniel J
Naval Medical Readiness and Training Center, Lemoore, CA; and.
Vanderbilt University Medical Center, Nashville, TN.
OTA Int. 2023 Jul 11;6(4 Suppl):e247. doi: 10.1097/OI9.0000000000000247. eCollection 2023 Jul.
The use of negative pressure wound therapy (NPWT) continues to be an important tool for surgeons. As the use and general acceptance of NPWT have grown, so have the indications for its use. These indications have expanded to include soft tissue defects in trauma, infection, surgical wound management, and soft tissue grafting procedures. Many adjuvants have been engineered into newer generations of NPWT devices such as wound instillation of fluid or antibiotics allowing surgeons to further optimize the wound healing environment or aid in the eradication of infection. This review discusses the recent relevant literature on the proposed mechanisms of action, available adjuvants, and the required components needed to safely apply NPWT. The supporting evidence for the use of NPWT in traumatic extremity injuries, infection control, and wound care is also reviewed. Although NPWT has a low rate of complication, the surgeon should be aware of the potential risks associated with its use. Furthermore, the expanding indications for the use of NPWT are explored, and areas for future innovation and research are discussed.
负压伤口治疗（NPWT）的应用仍然是外科医生的一项重要工具。随着NPWT的应用及其被普遍接受程度的提高，其使用指征也在增加。这些指征已扩展到包括创伤、感染、手术伤口处理和软组织移植手术中的软组织缺损。许多辅助装置已被设计到新一代的NPWT设备中，如伤口内液体或抗生素滴注，使外科医生能够进一步优化伤口愈合环境或帮助根除感染。本综述讨论了近期关于NPWT作用机制、可用辅助装置以及安全应用NPWT所需组件的相关文献。还综述了NPWT用于创伤性肢体损伤、感染控制和伤口护理的支持证据。尽管NPWT的并发症发生率较低，但外科医生应意识到其使用可能存在的风险。此外，还探讨了NPWT使用指征的扩展情况，并讨论了未来创新和研究的领域。
