[具体物质名称1]和[具体物质名称2]生物表面活性剂对[细菌名称1]和[细菌名称2]的细菌黏附抑制及抗生物膜作用。
Inhibition of bacterial adhesion and anti-biofilm effects of and biosurfactants against and .
作者信息
Keyhanian Alireza, Mohammadimehr Mojgan, Nojoomi Farshad, Naghoosi Hamed, Khomartash Mehdi Shakouri, Chamanara Mohsen
机构信息
Infectious Diseases Research Center, Aja University of Medical Sciences, Tehran, Iran.
Medical Biotechnology Research Center, Aja University of Medical Sciences, Tehran, Iran.
出版信息
Iran J Microbiol. 2023 Jun;15(3):425-432. doi: 10.18502/ijm.v15i3.12903.
BACKGROUND AND OBJECTIVES
Biosurfactants are amphiphilic surface-active agents that mainly produced by various microorganisms. In this study, the anti-biofilm and inhibition of bacterial adhesion activities of two bacterial biosurfactants were investigated.
MATERIALS AND METHODS
After extraction and evaluation of and biosurfctants, inhibition of bacterial adhesion and anti-biofilm effects of them on and were determined.
RESULTS
On average, the synergistic effect of two bacterial biosurfactants, caused about 60% decrease in adhesion and about 80% decrease in biofilm formation of and .
CONCLUSION
The results of this study showed that combination of and biosurfactants would increase the potential of attachment inhibition and biofilm eradication with very low toxicity.
背景与目的
生物表面活性剂是主要由各种微生物产生的两亲性表面活性剂。在本研究中，对两种细菌生物表面活性剂的抗生物膜和抑制细菌黏附活性进行了研究。
材料与方法
在提取和评估两种生物表面活性剂后，测定了它们对两种细菌的抑制细菌黏附及抗生物膜作用。
结果
平均而言，两种细菌生物表面活性剂的协同作用使两种细菌的黏附减少约60%，生物膜形成减少约80%。
结论
本研究结果表明，两种生物表面活性剂联合使用可提高抑制黏附及消除生物膜的潜力，且毒性极低。
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