Department of Surgery, CMH Specialist Hospital, Seremban, 70200, Negeri Sembilan, Malaysia.
Department of Cardiothoracic Surgery, National Heart Institute (IJN), 50400, Kuala Lumpur, Malaysia.
Ghana Med J. 2022 Jun;56(2):95-99. doi: 10.4314/gmj.v56i2.6.
To evaluate a newly developed, self-expandable anti-reflux Trumpet (ART) stent customized for cardio oesophageal junctional (COJ) cancer on the feasibility of deployment, stent migration, quality of life, and symptom relief.
Prospective case series, Proof of concept pilot study.
Tertiary Health Care Center, Hospital Tuanku Jaafar, Seremban, Malaysia. Department of Surgery.
A total of 17 patients diagnosed with advanced COJ tumour and who had never undergone any surgical, endoscopic, or chemoradiotherapy and indicated for stenting were recruited.
The study period was over nine months, and follow-up was one-month post-stenting.
Endpoint measures were feasibility of deployment of the new design, symptoms relief, early stent migration, early complication, GERD Q score, and (QOL)assessment.
The ART stent was inserted successfully in all cases (17/17, 100%). There were two stent migrations due to the flexibility of the stent at the neck. There were no early or post-stenting one-month complications associated with the procedure. A good flow of contrast was seen in all the stents deployed. GERD Q score was low in all patients pre and post-stenting. Post-stenting there was a relief of dysphagia, weight gain, and a 60% improvement in QOL score.
ART stent is feasible and technically successful in COJ tumours. It provides good symptom relief, improves the QOL, and has minimal early complications.
None declared.
评估一种新开发的、自扩张的抗反流 Trumpet（ART）支架，该支架专为心食管交界处（COJ）癌症定制，以评估其部署的可行性、支架迁移、生活质量和症状缓解。
前瞻性病例系列，概念验证性初步研究。
马来西亚 Seremban 的 Tuanku Jaafar 三级医疗中心，外科系。
共招募了 17 名诊断为晚期 COJ 肿瘤且从未接受过任何手术、内镜或放化疗且需要支架置入的患者。
研究期间为九个月，支架置入后一个月进行随访。
新设计的部署可行性、症状缓解、早期支架迁移、早期并发症、GERD Q 评分和（QOL）评估。
ART 支架在所有病例中均成功插入（17/17，100%）。由于支架在颈部的灵活性，有两例支架迁移。与该手术相关的无早期或支架置入后一个月并发症。所有置入的支架均可见造影剂良好流动。所有患者在支架置入前后的 GERD Q 评分均较低。支架置入后，吞咽困难、体重增加得到缓解，生活质量评分提高了 60%。
ART 支架在心食管交界处肿瘤中是可行的，技术上是成功的。它提供了良好的症状缓解，改善了生活质量，并且早期并发症很少。
无。
