系统免疫炎症指数与经皮冠状动脉介入治疗隐静脉桥无复流的关系。
Relationship between systemic immune-inflammation index and no-reflow in percutaneous coronary intervention for saphenous grafts.
机构信息
University of Health Sciences, Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
Department of Cardiology, Istinye University, Liv Bahçeşehir Hospital, Istanbul, 34303, Turkey.
出版信息
Biomark Med. 2023 Apr;17(8):427-435. doi: 10.2217/bmm-2023-0208. Epub 2023 Jul 14.
In this study, we investigated the occurrence of no-reflow (NR) in percutaneous coronary intervention (PCI) for saphenous vein grafts (SVGs) and its relationship with a new systemic immune-inflammation index (SII) that determines inflammation. We studied 303 patients with acute coronary syndrome without ST elevation who underwent PCI for SVG disease. NR formation during SVG PCI was significantly higher in patients with high SII (p < 0.001). NR occurrence was 12.8% when SII was ≤548 and 41.9% when SII was >548. Our study is the first to investigate SII as the state of inflammation and its effect on the SVG PCI. Patients with higher SII have a higher risk of NR during an SVG for PCI.
在这项研究中，我们调查了经皮冠状动脉介入治疗（PCI）中隐静脉桥（SVG）无复流（NR）的发生情况及其与一种新的全身性免疫炎症指数（SII）的关系，该指数可确定炎症。我们研究了 303 名患有急性冠状动脉综合征且无 ST 段抬高的患者，这些患者因 SVG 疾病而行 PCI。在 SII 较高的患者中，SVG PCI 期间 NR 形成的发生率明显更高（p < 0.001）。当 SII ≤548 时，NR 发生率为 12.8%，而当 SII >548 时，NR 发生率为 41.9%。我们的研究首次将 SII 作为炎症状态及其对 SVG PCI 的影响进行了研究。SII 较高的患者在 SVG 行 PCI 期间发生 NR 的风险更高。
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