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[氩激光与微动脉焊接]

[Argon laser and microarterial soldering].

作者信息

Godlewski G, Rouy S, Pradal P, Dauzat M

出版信息

J Chir (Paris). 1986 May;123(5):347-51.

PMID:3745322
Abstract

Fifty Wistar rats were submitted to a carotid end-to-end microanastomosis by means of a Coherent 900 Argon Laser. The laser shots were of 300 mW in power output and 5 sec. in duration with an impact area of 150 microns in diameter. The anastomosis was obtained in 4 min. using on an average 19 impacts. The luminal patency was evaluated through doppler and angiography visualization regularly achieved from day 0 up to 7 months. Light, scanning electron microscopic and ultrastructural examinations revealed that, on day 0, endothelial damages never exceeded 100 microns in width in the vicinity of the anastomotic line. Collagenous denaturation was immediately observed in the media and adventitia. The fusion line became re-endothelialized from day 3 and a collagenous network was always present in the media on day 10. Furthermore a slight fibrosis of the adventitia increased the wall resistance. The patency rate was 76% complications such as disruption and aneurysm were due to the initial technical drawbacks.

摘要

50只Wistar大鼠通过相干900氩激光进行颈动脉端端显微吻合术。激光束输出功率为300 mW,持续时间为5秒,冲击面积直径为150微米。在4分钟内完成吻合,平均使用19次冲击。从第0天到7个月定期通过多普勒和血管造影可视化评估管腔通畅情况。光学、扫描电子显微镜和超微结构检查显示,在第0天,吻合线附近内皮损伤宽度从未超过100微米。立即观察到中膜和外膜的胶原变性。从第3天开始融合线重新内皮化,第10天时中膜始终存在胶原网络。此外,外膜轻微纤维化增加了管壁阻力。通畅率为76%,诸如破裂和动脉瘤等并发症是由于最初的技术缺陷所致。

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