Pribil S, Powers S K
J Neurosurg. 1985 Nov;63(5):771-5. doi: 10.3171/jns.1985.63.5.0771.
Microvascular end-to-end anastomoses of rat common carotid arteries measuring 0.6 to 0.7 mm in diameter were performed using an argon surgical laser system. Vascular bonding with the argon laser was accomplished in all cases. The anastomosed carotid artery segments were evaluated both angiographically and histologically at 1 day, 1 week, and 1 month after laser bonding. With increasing time after anastomosis, there was a trend toward increasing angiographically proven stenosis of the anastomotic segment and histologically demonstrated pseudoaneurysm formation of the vessel wall at the bonded site. Pseudoaneurysm formation was associated with a dense inflammatory response in the anastomotic vessel segment. In spite of excellent initial tissue bonding and vessel patency, the delayed results of progressive vessel wall disruption and segmental stenosis indicate that further experience in using the argon laser for vessel welding is needed before this method can be accepted as an alternative to current microvascular suture technique.
使用氩气外科激光系统对直径为0.6至0.7毫米的大鼠颈总动脉进行微血管端端吻合。在所有病例中均实现了氩激光血管粘合。在激光粘合后1天、1周和1个月，对吻合的颈动脉段进行血管造影和组织学评估。随着吻合后时间的增加，血管造影证实的吻合段狭窄有增加趋势，且组织学显示在粘合部位血管壁形成假性动脉瘤。假性动脉瘤形成与吻合血管段的密集炎症反应有关。尽管初始组织粘合良好且血管通畅，但血管壁进行性破坏和节段性狭窄的延迟结果表明，在该方法被接受为当前微血管缝合技术的替代方法之前，需要在使用氩激光进行血管焊接方面积累更多经验。
