Pediatric Urology Department, Emory University School of Medicine, Sandy Springs, GA; Pediatric Urology Department, Children's Healthcare of Atlanta, Atlanta, GA.
Hematology/Oncology Department, Emory University School of Medicine, Sandy Springs, GA; Hematology/Oncology Department, Children's Healthcare of Atlanta, Atlanta, GA.
Urology. 2023 Nov;181:136-140. doi: 10.1016/j.urology.2023.06.018. Epub 2023 Jul 14.
Rhabdomyosarcoma (RMS) treatment involves surgery, chemotherapy, and radiotherapy. A radioprotective space between the bladder/prostate and rectum reduces postradiation complications, as reported in adult patients. Describe pediatric preradiotherapy perirectal hyaluronic acid (HA) spacer injection for bladder/prostate RMS. We present a case of a 17-month-old male with bladder/prostate RMS. Before radiotherapy, an HA spacer was injected peri-rectally. Under general anesthesia, a transrectal ultrasound was positioned and 1mL of HA spacer was injected into the perirectal space. No complications were reported at 6-month follow-up. This is the first report of pre-radiation therapy spacer injection for pediatric bladder/prostate RMS.
横纹肌肉瘤 (RMS) 的治疗包括手术、化疗和放疗。有报道称，在成人患者中，膀胱/前列腺和直肠之间的放射防护空间可减少放疗后的并发症。描述小儿膀胱/前列腺 RMS 放疗前直肠周围透明质酸 (HA) 隔离剂注射。我们报告了一例 17 个月大的男性膀胱/前列腺 RMS 病例。在放疗前，HA 隔离剂被直肠周围注射。在全身麻醉下，经直肠超声定位，将 1mL HA 隔离剂注入直肠周围间隙。6 个月随访时无并发症报告。这是首例小儿膀胱/前列腺 RMS 放疗前应用隔离剂的报道。
